3-(2-Iodoacetamido)-PROXYL
3-(2-Iodoacetamido)-PROXYL (CAS: 27048-01-7) is a stable free radical used as a spin label. With the molecular formula C10H18IN2O2 and a molecular weight of 325.17 g/mol, this compound is particularly effective for labeling sulfhydryl groups. Its applications extend to studies involving erythrocyte membrane proteins, myosin subfragment orientation, and the labeling of DNA fragments containing phosphorothioate diesters.
- IUPAC
- 3-(2-Iodoacetamido)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy, free radical
- Synonyms
- 3-(2-Iodoacetamido)-2,2,5,5-tetramethyl-1-pyrrolidinyloxy, free radical

Sulfhydryl Group Labeling
This compound serves as a specific spin label for sulfhydryl (-SH) groups in biological molecules, enabling the study of their environment and dynamics.
Erythrocyte Membrane Protein Studies
It has been utilised to investigate ozone-treated human and bovine erythrocyte membrane proteins, providing insights into structural changes and interactions.
Myosin Subfragment Orientation
Applications include determining the orientation of myosin subfragment on muscle fibers, contributing to the understanding of muscle contraction mechanisms.
DNA Fragment Labeling
3-(2-Iodoacetamido)-PROXYL can be used to label DNA fragments that contain phosphorothioate diesters, aiding in structural and functional analyses.
| Molecular weight | 325.17 |
|---|---|
| Empirical formula | C10H18IN2O2 |
| Storage temperature | 2-8°C |
| Application | Sulfhydryl group specific spin label. Applications include study of ozone-treated human and bovine erythrocyte membrane proteins and the orientation of myosin subfragment on muscle fibers. DNA fragments containing phosphorothioate diesters can be labeled by spin labels. |
| Melting point | 162-164 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(2-Iodoacetamido)-PROXYL used for?
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3-(2-Iodoacetamido)-PROXYL is primarily used as a sulfhydryl group specific spin label. It is applied in studies of erythrocyte membrane proteins, myosin subfragment orientation on muscle fibers, and for labeling DNA fragments containing phosphorothioate diesters.
What is the CAS number and molecular formula for 3-(2-Iodoacetamido)-PROXYL?
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The CAS number for 3-(2-Iodoacetamido)-PROXYL is 27048-01-7 and its molecular formula is C10H18IN2O2.
What grade and purity does Tech Serve Solutions supply for 3-(2-Iodoacetamido)-PROXYL?
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Tech Serve Solutions supplies this compound for research and chemical synthesis purposes. The specific grade and purity are available upon request, and it is not represented as USP, BP, or EP grade.
What are the safety and handling requirements for 3-(2-Iodoacetamido)-PROXYL?
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When handling 3-(2-Iodoacetamido)-PROXYL, appropriate personal protective equipment, including eyeshields and gloves, should be worn. A respirator filter such as type N95 (US) or type P1 (EN143) is recommended. The compound has a WGK Germany rating of 3, indicating a high hazard to water.
How is 3-(2-Iodoacetamido)-PROXYL stored and shipped?
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This compound should be stored at 2-8°C. Tech Serve Solutions ensures that all products are packed and exported in accordance with international regulations for hazardous materials.
How can I request a quote or sample for 3-(2-Iodoacetamido)-PROXYL?
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To request a quote or a sample of 3-(2-Iodoacetamido)-PROXYL, please contact our sales department through the website or by phone, providing your specific requirements.
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