(2S)-(+)-Glycidyl tosylate
(2S)-(+)-Glycidyl tosylate (CAS: 70987-78-9), a chiral epoxide with the formula C10H12O4S and a molecular weight of 228.26 g/mol, is a valuable building block in asymmetric synthesis. Its specific stereochemistry makes it ideal for constructing complex chiral molecules. TSS supplies this compound for research and chemical synthesis applications, ensuring high quality for demanding projects.
- IUPAC
- (S)-(+)-Glycidyl p-toluenesulfonate,(S)-(+)-Oxirane-2-methanol p-toluenesulfonate
Asymmetric Synthesis
Utilised as a chiral building block in enantioselective synthesis pathways. It plays a crucial role in the construction of stereochemically defined organic molecules, particularly in pharmaceutical research and development.
Epoxide Chemistry
Serves as a reactive epoxide intermediate for introducing chiral glycidyl moieties into various organic structures. Its tosylate leaving group facilitates nucleophilic substitution reactions.
Synthesis of Heterocycles
Employed in the synthesis of complex heterocyclic compounds, such as the reported use in the enantioselective synthesis of specific pyrido[3,2-b]oxazines.
| Molecular weight | 228.26 |
|---|---|
| Empirical formula | C10H12O4S |
| Assay | 98% |
| Storage temperature | 2-8°C |
| Application | Used in the first enantioselective synthesis of (R)- and (S)-4-acetyl-3-(hydroxymethyl)-3,4-dihydro-2H-pyrido[3,2-b]oxazines.1 |
| Melting point | 46-49 °C(lit.) |
Hazard statements
- H317May cause an allergic skin reaction
- H318Causes serious eye damage
- H341Suspected of causing genetic defects
- H350May cause cancer
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P201Obtain special instructions before use
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P308IF exposed or concerned
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 45-41-43-51/53-68 |
| Safety statements (S) | 53-45-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2S)-(+)-Glycidyl tosylate used for?
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(2S)-(+)-Glycidyl tosylate is primarily used as a chiral building block in asymmetric synthesis, particularly in the creation of enantiomerically pure compounds and complex organic molecules.
What is the CAS number and chemical formula for (2S)-(+)-Glycidyl tosylate?
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The CAS number is 70987-78-9, and the chemical formula is C10H12O4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (2S)-(+)-Glycidyl tosylate with an assay of 98%. This product is not represented as USP, BP, EP, or any pharmacopoeia grade.
How should (2S)-(+)-Glycidyl tosylate be handled safely?
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This compound is classified as dangerous. It causes serious eye damage (H318), may cause an allergic skin reaction (H317), is suspected of causing genetic defects (H341), may cause cancer (H350), and is toxic to aquatic life with long lasting effects (H411). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, and avoid release into the environment.
Is (2S)-(+)-Glycidyl tosylate a controlled substance?
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The provided data does not indicate that (2S)-(+)-Glycidyl tosylate is a controlled substance.
How is (2S)-(+)-Glycidyl tosylate packed and shipped?
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(2S)-(+)-Glycidyl tosylate is suitable for export and is typically shipped under conditions that maintain its integrity. Specific packaging details are available upon request.
How can I request a quote or sample of (2S)-(+)-Glycidyl tosylate?
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To request a quote or sample of (2S)-(+)-Glycidyl tosylate, please contact our sales team via the website or your designated account manager.
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