(2S)-(+)-Glycidyl 4-nitrobenzoate
(2S)-(+)-Glycidyl 4-nitrobenzoate (CAS: 115459-65-9; Formula: C10H9NO5; MW: 223.18) is a chiral epoxide building block. This optically active compound is valuable in asymmetric synthesis for the construction of enantiomerically pure molecules. It serves as a versatile intermediate in organic synthesis, particularly in the pharmaceutical and fine chemical industries, enabling the introduction of chiral epoxy alcohol moieties into more complex structures.
- IUPAC
- (S)-(+)-Glycidyl 4-nitrobenzoate,(S)-(+)-Oxirane-2-methanol 4-nitrobenzoate
Asymmetric Synthesis
This compound is a key chiral building block utilised in asymmetric synthesis. Its epoxide functionality allows for stereoselective ring-opening reactions, leading to the formation of enantiomerically enriched products critical for pharmaceutical development.
Organic Synthesis Intermediate
As a versatile organic intermediate, (2S)-(+)-Glycidyl 4-nitrobenzoate is employed in the multi-step synthesis of complex organic molecules. Its specific stereochemistry and reactive epoxide group make it suitable for creating chiral alcohols and other functionalised compounds.
Pharmaceutical Research
This reagent finds application in pharmaceutical research and development. It can be used to synthesise potential drug candidates or intermediates where precise stereochemical control is paramount for biological activity.
| Molecular weight | 223.18 |
|---|---|
| Empirical formula | C10H9NO5 |
| Assay | 98% |
| Optical activity | [α]19/D +37°, c = 1.08 in chloroform |
| Storage temperature | 2-8°C |
| Melting point | 60-62 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2S)-(+)-Glycidyl 4-nitrobenzoate used for?
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(2S)-(+)-Glycidyl 4-nitrobenzoate is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in organic synthesis, particularly for creating enantiomerically pure compounds relevant to pharmaceutical research.
What is the CAS number and molecular formula?
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The CAS number for (2S)-(+)-Glycidyl 4-nitrobenzoate is 115459-65-9, and its molecular formula is C10H9NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (2S)-(+)-Glycidyl 4-nitrobenzoate with an assay of 98%. This is a technical/research grade chemical; TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should (2S)-(+)-Glycidyl 4-nitrobenzoate be handled?
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(2S)-(+)-Glycidyl 4-nitrobenzoate is a warning substance that causes skin irritation, serious eye irritation, and respiratory irritation (H315-H319-H335). When handling, use a dust mask type N95 (US), wear eyeshields, and gloves. Ensure adequate ventilation (P261, P338) and avoid breathing dust (P261).
Is (2S)-(+)-Glycidyl 4-nitrobenzoate suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including (2S)-(+)-Glycidyl 4-nitrobenzoate, and can fulfil international export orders.
How can I request a quote or sample for (2S)-(+)-Glycidyl 4-nitrobenzoate?
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To request a quote or sample, please visit the Tech Serve Solutions website or contact our sales team directly, referencing the product name and CAS number 115459-65-9.
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