(2S,3R,4S)-α-(Carboxycyclopropyl)glycine
(2S,3R,4S)-α-(Carboxycyclopropyl)glycine (CAS: 117857-95-1), with the molecular formula C6H9NO4 and a molecular weight of 159.14 g/mol, is a non-proteinogenic amino acid derivative. This compound is recognised for its specific stereochemistry and is primarily utilised in chemical biology and synthesis. Its applications span the development of novel peptides and the study of unnatural amino acid derivatives, making it a valuable reagent for advanced research.
- IUPAC
- (2S,1′R,2′S)-2-(2-Carboxycyclopropyl)glycine,(2S,3R,4S)-CCG,L-CCG-IV
- Synonyms
- 117857-95-1C6H9NO4(2S,1′R,2′S)-2-(2-Carboxycyclopropyl)glycine(2S,3R,4S)-CCGL-CCG-IV

Chemical Synthesis
Serves as a building block in the synthesis of complex organic molecules, particularly those involving modified amino acid structures. Its unique cyclopropyl group offers distinct reactivity and structural properties for synthetic chemists.
Chemical Biology Research
Used in studies investigating biological pathways and protein function where non-natural amino acids can probe or modulate molecular interactions. Its structure can be incorporated into peptides to alter conformational stability or binding affinity.
Peptide Chemistry
Incorporated into peptide sequences to create analogues with altered pharmacokinetic or pharmacodynamic properties. This is crucial for developing novel therapeutics or research tools.
Unnatural Amino Acid Studies
A key compound for researchers exploring the role and incorporation of unnatural amino acids into biological systems or synthetic constructs. It contributes to expanding the repertoire of amino acids available for biochemical research.
| Molecular weight | 159.14 |
|---|---|
| Empirical formula | C6H9NO4 |
| Solubility | H2O: soluble |
| Optical activity | [α]/D +69.5°, c = 0.4 in H2O(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2S,3R,4S)-α-(Carboxycyclopropyl)glycine used for?
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This compound is primarily used in chemical biology and chemical synthesis, particularly for the study and development of unnatural amino acid derivatives and modified peptides.
What is the CAS number and chemical formula for (2S,3R,4S)-α-(Carboxycyclopropyl)glycine?
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The CAS number is 117857-95-1 and the chemical formula is C6H9NO4.
What grade and purity does Tech Serve Solutions supply for (2S,3R,4S)-α-(Carboxycyclopropyl)glycine?
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Tech Serve Solutions supplies (2S,3R,4S)-α-(Carboxycyclopropyl)glycine as a research-grade chemical. We do not represent it as USP, BP, or EP grade.
How should (2S,3R,4S)-α-(Carboxycyclopropyl)glycine be handled?
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Appropriate personal protective equipment, including eyeshields and gloves, should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Please consult the safety data sheet for comprehensive handling information.
Is (2S,3R,4S)-α-(Carboxycyclopropyl)glycine a controlled substance?
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The provided data does not indicate that (2S,3R,4S)-α-(Carboxycyclopropyl)glycine is a controlled substance.
How is (2S,3R,4S)-α-(Carboxycyclopropyl)glycine packed and shipped?
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We ensure products are securely packed for domestic and international export, adhering to all relevant shipping regulations for chemical compounds.
How can I request a quote or sample for (2S,3R,4S)-α-(Carboxycyclopropyl)glycine?
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Please use the contact form on our website or contact our sales team directly to request a quote or a sample of (2S,3R,4S)-α-(Carboxycyclopropyl)glycine.
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