(2S,3R)-3-(Boc-amino)-2-hydroxy-4-phenylbutyric acid
(2S,3R)-3-(Boc-amino)-2-hydroxy-4-phenylbutyric acid (CAS 62023-65-8) is a protected beta-amino acid derivative with the empirical formula C15H21NO5 and a molecular weight of 295.33 g/mol. It serves as a crucial building block in organic synthesis, particularly for the preparation of bestatin and related analogues. This compound finds application in research focusing on peptide chemistry and the development of novel bioactive molecules.
- IUPAC
- Boc-(2S,3R)-3-amino-2-hydroxy-4-phenylbutyric acid
- Synonyms
- Boc-(2S,3R)-3-amino-2-hydroxy-4-phenylbutyric acid

Preparation of Bestatin Analogues
This compound is a key intermediate for the synthesis of bestatin, a potent aminopeptidase inhibitor. Its specific stereochemistry allows for the precise construction of complex analogues with modified biological activities.
Peptide Synthesis
As an unnatural amino acid derivative, it can be incorporated into peptide chains to introduce unique structural features or functionalities. This is valuable in the design of peptidomimetics and modified peptides for research.
Chemical Biology Research
Used as a research chemical in studies exploring enzyme inhibition and structure-activity relationships. Its availability facilitates the investigation of biological pathways and the development of potential therapeutic agents.
Organic Synthesis Intermediate
A versatile building block for academic and industrial research laboratories involved in the synthesis of complex organic molecules. It provides a chiral scaffold for further chemical transformations.
| Molecular weight | 295.33 |
|---|---|
| Empirical formula | C15H21NO5 |
| Assay | ≥98.0% (TLC) |
| Application | Novel protected amino acid for the preparation of bestatin and analogs. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (2S,3R)-3-(Boc-amino)-2-hydroxy-4-phenylbutyric acid used for?
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It is primarily used as an intermediate for the preparation of bestatin and its analogues, and in peptide chemistry and general organic synthesis research.
What are the CAS number and empirical formula for this compound?
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The CAS number is 62023-65-8, and the empirical formula is C15H21NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥98.0% (TLC). We do not represent it as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
What are the safety and handling recommendations?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound is classified under WGK Germany 3, indicating a significant hazard to water.
How is this chemical shipped or exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, capable of handling international shipments according to regulations.
How can I request a sample or quote?
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Please contact our sales team via the website or direct inquiry channels to request a sample or obtain a quotation for (2S,3R)-3-(Boc-amino)-2-hydroxy-4-phenylbutyric acid.
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