25-Hydroxycholecalciferol
25-Hydroxycholecalciferol (CAS: 19356-17-3, C27H44O2) is a key metabolite of Vitamin D3, with a molecular weight of 400.64 g/mol. It plays a crucial role in calcium and phosphate homeostasis, influencing bone health and immune function. This compound is widely utilised in biochemical research and nutritional studies, serving as a vital tool for investigating vitamin D metabolism and its physiological effects.
- IUPAC
- 25-Hydroxyvitamin D3
- Synonyms
- 25-Hydroxyvitamin D3Calcifediol
Nutritional Research
25-Hydroxycholecalciferol is fundamental in studies investigating vitamin D metabolism and its impact on calcium absorption and bone mineralisation. It serves as a marker for vitamin D status and is used to understand the efficacy of vitamin D supplementation.
Cell Biology Studies
This metabolite is employed in cell-based assays to explore the non-skeletal actions of vitamin D, including its roles in immune modulation, cell proliferation, and differentiation. It aids in understanding signalling pathways regulated by vitamin D.
Biochemical Research
As a critical intermediate in vitamin D activation, 25-Hydroxycholecalciferol is used to study enzymatic processes and metabolic pathways related to vitamin D. Researchers utilise it to investigate the synthesis and degradation of active vitamin D forms.
Gene Regulation Research
The compound is applied in research focused on how vitamin D influences gene expression. It helps elucidate the mechanisms by which vitamin D receptors interact with DNA to regulate the transcription of target genes.
| Molecular weight | 400.64 |
|---|---|
| Empirical formula | C27H44O2 |
| Assay | ≥98% (HPLC) |
| Storage temperature | −20°C |
Hazard statements
- H300Fatal if swallowed
- H310Fatal in contact with skin
- H330Fatal if inhaled
- H372Causes damage to organs through prolonged exposure
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 24/25-26-48/25 |
| Safety statements (S) | 28-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 25-Hydroxycholecalciferol used for?
+
25-Hydroxycholecalciferol is primarily used in nutritional research, cell biology, biochemical studies, and gene regulation research to investigate vitamin D metabolism and its physiological effects.
What are the CAS number and chemical formula for 25-Hydroxycholecalciferol?
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The CAS number for 25-Hydroxycholecalciferol is 19356-17-3, and its chemical formula is C27H44O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 25-Hydroxycholecalciferol with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 25-Hydroxycholecalciferol be handled and stored?
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25-Hydroxycholecalciferol is a highly toxic substance (Danger: H300-H310-H330-H372). Strict handling procedures are required, including the use of full-face particle respirators (type N100), safety goggles, face shields, and appropriate gloves. Store at -20°C.
Is 25-Hydroxycholecalciferol a controlled substance?
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Based on the provided data, there is no indication that 25-Hydroxycholecalciferol (CAS: 19356-17-3) is a controlled substance in standard chemical classifications. However, users should verify local regulations.
How is 25-Hydroxycholecalciferol packed and shipped?
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25-Hydroxycholecalciferol is shipped under UN 2811, Hazard Class 6.1, Packing Group II, indicating it is a toxic solid. Packaging and shipping adhere to strict international regulations for hazardous materials.
How can I request a quote or sample for 25-Hydroxycholecalciferol?
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To request a quote or sample, please contact our sales department through the TSS website or by phone, providing the product name and CAS number (19356-17-3).
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