2-((Trimethylsilyl)ethynyl)pyridin-3-ol
2-((Trimethylsilyl)ethynyl)pyridin-3-ol (CAS: 556832-92-9) is a pyridine derivative featuring a trimethylsilyl-protected ethynyl group and a hydroxyl substituent. With a molecular weight of 191.30 g/mol, this organosilicon compound serves as a valuable building block in organic synthesis. Its unique structure makes it suitable for applications in pharmaceutical research and the development of novel chemical entities, particularly within heterocyclic chemistry.

Organic Synthesis Intermediate
This compound acts as a key intermediate in complex organic syntheses, enabling the introduction of a functionalised pyridine ring into larger molecular frameworks. The trimethylsilyl group offers protection during reactions and can be readily removed when required.
Pharmaceutical Research
It is utilised in the discovery and development of new pharmaceutical agents. Its pyridine core is a common feature in many biologically active molecules, making this compound a useful precursor for medicinal chemistry programmes.
Heterocyclic Chemistry
As a functionalised pyridine, it is employed in studies and syntheses involving heterocyclic compounds, contributing to the expansion of chemical libraries and the exploration of novel molecular architectures.
Organosilicon Chemistry
The presence of the trimethylsilyl moiety positions this compound within the realm of organosilicon chemistry, offering unique reactivity and synthetic possibilities related to silicon-containing organic molecules.
| Molecular weight | 191.30 |
|---|---|
| Empirical formula | C10H13NOSi |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-((Trimethylsilyl)ethynyl)pyridin-3-ol used for?
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2-((Trimethylsilyl)ethynyl)pyridin-3-ol is primarily used as a building block in organic synthesis, particularly in pharmaceutical research and heterocyclic chemistry, due to its functionalised pyridine structure.
What are the CAS number and formula for this compound?
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The CAS number is 556832-92-9 and the empirical formula is C10H13NOSi.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific grade and purity are available upon request and are not represented as USP, BP, or EP grade.
How should 2-((Trimethylsilyl)ethynyl)pyridin-3-ol be handled and stored?
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Specific safety data sheets (SDS) should be consulted for detailed handling and storage information. Generally, it should be handled in a well-ventilated area, avoiding contact with skin, eyes, and clothing. Store in a cool, dry place.
Is this compound available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and laboratory reagents, including 2-((Trimethylsilyl)ethynyl)pyridin-3-ol.
How can I request a quote or sample?
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Please contact our sales team via the website or by phone to request a quotation or a sample of 2-((Trimethylsilyl)ethynyl)pyridin-3-ol.
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