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2-((tert-Butyldimethylsilanyl)ethynyl) boronic acid pinacol ester

CAS 1073355-02-8C14H27BO2SiChemical Synthesis

2-((tert-Butyldimethylsilanyl)ethynyl) boronic acid pinacol ester (CAS: 1073355-02-8; Formula: C14H27BO2Si; MW: 266.26) is a versatile organoboron compound. It features a protected alkyne and a boronate ester moiety, making it valuable in organic synthesis. This reagent is commonly employed in cross-coupling reactions, particularly Suzuki-Miyaura couplings, for the formation of carbon-carbon bonds in the synthesis of complex organic molecules.

IUPAC
2-((tert-Butyldimethylsilanyl)ethynyl)-4,4,5,5-tetramethyl-(1,3,2)dioxaborolane,2-[2-[(1,1-Dimethylethyl)dimethylsilyl]ethynyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Synonyms
2-[2-[(1,1-Dimethylethyl)dimethylsilyl]ethynyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane2-((tert-Butyldimethylsilanyl)ethynyl)-4,4,5,5-tetramethyl-(1,3,2)dioxaborolane
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2-((tert-Butyldimethylsilanyl)ethynyl) boronic acid pinacol ester (C14H27BO2Si) — chemical structure, CAS 1073355-02-8; Chemistry, fine chemical supplied by Tech Serve Solutions
Alkynyl Boronate EstersBoronate EstersChemical SynthesisOrganometallic Reagents
01 /Applications

Suzuki-Miyaura Cross-Coupling

This compound serves as a key building block in Suzuki-Miyaura cross-coupling reactions. It enables the efficient synthesis of internal alkynes and conjugated systems by coupling with aryl or vinyl halides.

Organic Synthesis Intermediate

Its unique structure, combining a silyl-protected alkyne and a boronate ester, makes it a useful intermediate for constructing complex molecular architectures in medicinal chemistry and materials science.

Alkynylation Reactions

The alkynyl group can be readily deprotected and further functionalized, while the boronate ester allows for selective coupling, offering versatility in synthetic strategies.

02 /Properties
Molecular weight266.26
Empirical formulaC14H27BO2Si
Assay97%
Storage temperature−20°C
Melting point159-164 °C
03 /Identifiers & registry
CAS number
1073355-02-8
MDL number
MFCD09265092
04 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is 2-((tert-Butyldimethylsilanyl)ethynyl) boronic acid pinacol ester used for?

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This compound is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds, and in the synthesis of complex organic molecules.

What is the CAS number and formula for 2-((tert-Butyldimethylsilanyl)ethynyl) boronic acid pinacol ester?

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The CAS number is 1073355-02-8 and the empirical formula is C14H27BO2Si.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this product with a purity of 97%. We do not represent this product as USP, BP, or EP grade.

What are the safety and handling precautions for this chemical?

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This chemical is classified as hazardous. It is recommended to handle it in a well-ventilated area, wear appropriate personal protective equipment (gloves, eye protection), and avoid inhalation or contact with skin and eyes. Refer to the Safety Data Sheet for detailed information.

How is 2-((tert-Butyldimethylsilanyl)ethynyl) boronic acid pinacol ester packaged and shipped?

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This product is typically stored at -20°C. Tech Serve Solutions, as a global supplier and exporter, ensures appropriate packaging and documentation for international shipment in compliance with all regulations.

How can I request a sample or a quote?

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Please contact our sales team via the website or by phone to request a sample or a quote for 2-((tert-Butyldimethylsilanyl)ethynyl) boronic acid pinacol ester.

Need 2-((tert-Butyldimethylsilanyl)ethynyl) boronic acid pinacol ester in a specific grade or volume?