2-Pyrrolidinone
2-Pyrrolidinone (CAS: 616-45-5, C4H7NO, MW: 85.10) is a versatile organic compound, a cyclic amide known for its excellent solvency and hygroscopic properties. It serves as a key intermediate in chemical synthesis and is utilized in diverse industrial applications. 2-Pyrrolidinone is recognized for its role as a building block in organic chemistry and its potential in cell biology research.
- IUPAC
- 2-Pyrrolidone,Butyrolactam
- Synonyms
- 2-PyrrolidoneButyrolactam

Solvent Applications
2-Pyrrolidinone is a highly effective polar aprotic solvent, miscible with water and many organic solvents. It is employed in industrial processes such as gas sweetening, textile processing, and as a solvent for polymers and resins.
Chemical Intermediate
This compound acts as a crucial building block in the synthesis of various chemicals, including pharmaceuticals, agrochemicals, and polymers. Its reactive nature allows for its incorporation into more complex molecular structures.
Industrial Cleaning
Due to its strong solvency, 2-Pyrrolidinone finds use in industrial cleaning formulations, particularly for removing coatings, resins, and greases.
Research and Development
In laboratory settings, 2-Pyrrolidinone is utilized in research for organic synthesis, and its properties are investigated in areas such as cell biology.
| Molecular weight | 85.10 |
|---|---|
| Empirical formula | C4H7NO |
| Assay | ≥99% |
| Grade | purum |
| Boiling point | 245 °C(lit.) |
| Density | 1.12 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.487(lit.) |
| Melting point | 23-25 °C(lit.) |
| Solubility | benzene: miscible(lit.)carbon disulfide: miscible(lit.)chloroform: miscible(lit.)diethyl ether: miscible(lit.)ethanol: miscible(lit.)ethyl acetate: miscible(lit.)water: miscible(lit.) |
| Vapour density | 2.9 (vs air) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | rat ... Gabra2(29706) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Pyrrolidinone used for?
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2-Pyrrolidinone is used as a versatile polar aprotic solvent, a key intermediate in chemical synthesis for pharmaceuticals and agrochemicals, in industrial cleaning, and in research.
What is the CAS number and formula for 2-Pyrrolidinone?
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The CAS number for 2-Pyrrolidinone is 616-45-5, and its empirical formula is C4H7NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Pyrrolidinone with an assay of ≥99% and a 'purum' grade. This product is not represented as USP, BP, or EP grade.
What are the safety and handling considerations for 2-Pyrrolidinone?
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2-Pyrrolidinone requires appropriate personal protective equipment, including eyeshields and gloves. Respiratory protection such as a type N95 (US) or type P1 (EN143) respirator filter is recommended. It has a flash point of 113 °C (235.4 °F).
How is 2-Pyrrolidinone typically packed and shipped?
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2-Pyrrolidinone is carefully packed for secure transit and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a quote or sample of 2-Pyrrolidinone?
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To request a quote or a sample of 2-Pyrrolidinone, please contact our sales team through the website or via the provided contact details.
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