2-Pyridylzinc bromide solution
2-Pyridylzinc bromide solution (CAS 218777-23-2, C5H4BrNZn, MW 223.39) is a valuable organozinc reagent supplied by Tech Serve Solutions. This solution, typically at 0.5 M in THF and stored at 2-8°C, is primarily utilised in advanced chemical synthesis. It plays a role in the preparation of specific ligands for catalytic reactions, contributing to the development of new chemical entities and processes.
Preparation of P,N Ligands
This organozinc reagent is specifically employed in synthesising P,N ligands. These ligands are critical components in asymmetric iridium-catalyzed reactions, enabling stereoselective synthesis.
Organometallic Synthesis
As an organozinc halide, it functions as a versatile building block in organometallic chemistry. It facilitates carbon-carbon bond formation through various cross-coupling reactions.
Heteroaryl Compound Synthesis
Its structure makes it suitable for introducing the 2-pyridyl moiety into complex organic molecules. This is important for creating novel heteroaromatic compounds with potential applications in pharmaceuticals and materials science.
| Molecular weight | 223.39 |
|---|---|
| Empirical formula | C5H4BrNZn |
| Density | 0.974 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
| Application | Used in the preparation of P,N ligands for asymmetric Ir-catalyzed reactions.1 |
Hazard statements
- H225Highly flammable liquid and vapour
- H261In contact with water releases flammable gas
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P422
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -17 °C / 1.4 °F |
| Transport (UN / ADR) | UN 3399 4.3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14/15-19-34-37 |
| Safety statements (S) | 16-26-36/37/39-43-45 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Pyridylzinc bromide solution used for?
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2-Pyridylzinc bromide solution (CAS 218777-23-2) is used in chemical synthesis, particularly for preparing P,N ligands employed in asymmetric Ir-catalyzed reactions, and as a building block in organometallic chemistry.
What are the CAS number and formula for 2-Pyridylzinc bromide solution?
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The CAS number for 2-Pyridylzinc bromide solution is 218777-23-2, and its empirical formula is C5H4BrNZn.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Pyridylzinc bromide solution at a concentration of 0.5 M in THF. TSS does not represent this product as USP, BP, or EP grade; it is intended for research and synthesis purposes.
How should 2-Pyridylzinc bromide solution be handled and stored?
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2-Pyridylzinc bromide solution is highly flammable and water-reactive, and can cause severe skin burns and eye damage. It may also form explosive peroxides. Handle under an inert atmosphere, wear appropriate personal protective equipment including eyeshields, gloves, and a suitable respirator. Store refrigerated at 2-8°C away from ignition sources and moisture.
Is 2-Pyridylzinc bromide solution packed or shipped internationally?
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Yes, Tech Serve Solutions specialises in global supply and export of fine chemicals, including 2-Pyridylzinc bromide solution, adhering to international shipping regulations.
How can I request a quote or sample for 2-Pyridylzinc bromide solution?
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To request a quote or a sample of 2-Pyridylzinc bromide solution, please contact our sales team via the website or direct email, providing your contact details and required quantity.
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