2-Phenylglycine
2-Phenylglycine (CAS 2835-06-5) is an unnatural amino acid derivative with the linear formula C<sub>6</sub>H<sub>5</sub>CH(NH<sub>2</sub>)COOH and a molecular weight of 151.16 g/mol. This chiral compound is a valuable building block in organic synthesis. Its primary applications lie in chemical biology, peptide chemistry, and the development of phenylglycine derivatives, serving as a key intermediate in various synthetic pathways.
- IUPAC
- (±)-α-Aminophenylacetic acid,DL-α-Phenylglycine

Chemical Synthesis
2-Phenylglycine is utilised as a versatile chiral building block in the synthesis of complex organic molecules. Its structure allows for the introduction of a phenyl group and an amino acid moiety into target compounds.
Peptide Chemistry
As an unnatural amino acid, 2-Phenylglycine can be incorporated into peptides to modify their structure and properties. This is useful in the design of novel peptides with enhanced stability or specific biological activities.
Chemical Biology
The compound finds application in chemical biology for creating labelled molecules or probes. It serves as a starting material for synthesizing compounds used to study biological processes.
Derivative Development
2-Phenylglycine acts as a precursor for a range of phenylglycine derivatives, which are explored for various applications in medicinal chemistry and materials science.
| Molecular weight | 151.16 |
|---|---|
| Linear formula | C6H5CH(NH2)COOH |
| Assay | 95% |
| Melting point | 290 °C (subl.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Phenylglycine used for?
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2-Phenylglycine is primarily used in chemical synthesis, peptide chemistry, chemical biology, and for developing phenylglycine derivatives.
What is the CAS number and formula for 2-Phenylglycine?
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The CAS number for 2-Phenylglycine is 2835-06-5 and its linear formula is C<sub>6</sub>H<sub>5</sub>CH(NH<sub>2</sub>)COOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Phenylglycine with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
How should 2-Phenylglycine be handled safely?
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Handling 2-Phenylglycine requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the safety data sheet for comprehensive handling instructions.
Is 2-Phenylglycine a controlled substance?
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The provided data does not indicate that 2-Phenylglycine is a controlled substance.
How is 2-Phenylglycine packed, shipped, and exported?
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Tech Serve Solutions adheres to stringent packaging and shipping regulations for chemical products, ensuring safe handling and export compliance.
How can I request a sample or quote for 2-Phenylglycine?
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To request a sample or quote for 2-Phenylglycine, please contact our sales department through the website or directly via email or phone.
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