2-Phenylbutyronitrile
2-Phenylbutyronitrile (CAS 769-68-6), with the molecular formula C6H5CH(CH2CH3)CN and a molar mass of 145.20 g/mol, is a valuable organic building block. This nitrile compound is synthesised for use in chemical reactions. It is supplied by Tech Serve Solutions with an assay of 95%, suitable for various chemical synthesis applications in research and development settings.
- IUPAC
- α-Ethylphenylacetonitrile
Preparation of Michael Adducts
2-Phenylbutyronitrile has been employed in the synthesis of Michael adducts, which are important intermediates in organic chemistry. Its reactivity allows for the formation of new carbon-carbon bonds.
Synthesis of S-Amides
This compound serves as a substrate for the preparation of S-amides through the action of nitrile hydratase enzymes. This application highlights its utility in biocatalytic transformations.
Organic Synthesis Intermediate
As a versatile building block, 2-Phenylbutyronitrile is utilised in a range of organic synthesis pathways. Its nitrile functionality and chiral centre offer opportunities for diverse chemical modifications.
| Molecular weight | 145.20 |
|---|---|
| Linear formula | C6H5CH(CH2CH3)CN |
| Assay | 95% |
| Boiling point | 114-115 °C/15 mmHg(lit.) |
| Density | 0.974 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5086(lit.) |
| Application | 2-Phenylbutyronitrile was used in the preparation of Michael-adducts1. It was also used in the preparation of S-amides by nitrile hydratase2. |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 105 °C / 221 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Phenylbutyronitrile used for?
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2-Phenylbutyronitrile is used as a building block in organic synthesis, including the preparation of Michael adducts and S-amides.
What are the CAS number and molecular formula for 2-Phenylbutyronitrile?
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The CAS number for 2-Phenylbutyronitrile is 769-68-6, and its molecular formula is C6H5CH(CH2CH3)CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Phenylbutyronitrile with an assay of 95%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety considerations for handling 2-Phenylbutyronitrile?
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2-Phenylbutyronitrile is classified as harmful if swallowed, in contact with skin, or if inhaled (H302-H312-H332). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, must be used. Consult the Safety Data Sheet for full handling instructions.
Is 2-Phenylbutyronitrile a controlled substance?
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The provided data does not indicate that 2-Phenylbutyronitrile is a controlled substance.
How is 2-Phenylbutyronitrile packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports chemicals according to international regulations and customer requirements. Please contact us for specific details regarding packaging and shipping options for 2-Phenylbutyronitrile.
How can I request a quote or sample for 2-Phenylbutyronitrile?
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To request a quote or a sample of 2-Phenylbutyronitrile, please contact the Tech Serve Solutions sales department via our website or by phone.
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