2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine

CAS 26853-31-6C42H82NO8PBiochemicals & Reagents

2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine (CAS: 26853-31-6), with the molecular formula C42H82NO8P, is a vital glycerophospholipid. This compound plays a crucial role in cell membrane structure and function. It is extensively used in biochemical research, particularly for studying lipid-protein interactions, membrane biophysics, and as a component in liposome formulations for drug delivery systems and nanotechnology applications like nanodiscs.

IUPAC: (7R,17Z)-4-Hydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxohexadecyl)oxy]methyl]-3,5,8-trioxa-4-phosphahexacos-17-en-1-aminium 4-oxide, inner salt,1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine,1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine,1-Hexadecanoyl-2-(cis-9-octadecenoyl)-sn-glycero-3-phosphocholine,3-sn-Phosphatidylcholine, 2-oleoyl-1-palmitoyl,L-β-Oleoyl-γ-palmitoyl-α-lecithin,PC(16:0/18:1(9Z)),PC(16:0/18:1),PC(16:0/18:1w9),POPC
Synonyms: 1-Hexadecanoyl-2-(cis-9-octadecenoyl)-sn-glycero-3-phosphocholine1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholinePOPCPC(16:0/18:1(9Z))PC(16:0/18:1w9)PC(16:0/18:1)3-sn-Phosphatidylcholine, 2-oleoyl-1-palmitoylL-β-Oleoyl-γ-palmitoyl-α-lecithin

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2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine (C42H82NO8P) — chemical structure, CAS 26853-31-6; Life Science, fine chemical supplied by Tech Serve Solutions

Biochemicals and ReagentsCell BiologyGlycerophospholipidsGlycerophosphonocholinesLipidsMetabolic PathwaysMetabolomics

01 /Applications

Liposome and Nanodisc Formulation

This phospholipid is a key component in the preparation of liposomes and nanodiscs. These structures are essential tools for membrane protein research, solubilisation, and stabilisation, facilitating studies into protein function and interactions within a lipid bilayer environment.

Membrane Biophysics Research

Used to investigate the physical properties of biological membranes, including fluidity, permeability, and phase transitions. Its defined structure allows researchers to model natural cell membranes and understand their behaviour under various conditions.

Biochemical and Cell Biology Studies

Serves as a research reagent for exploring glycerophospholipid metabolism and other cellular pathways. Its involvement in cellular processes makes it valuable for understanding cell signalling and membrane trafficking.

02 /Properties

Molecular weight	760.08
Empirical formula	C42H82NO8P
Assay	≥99.0% (TLC)
Storage temperature	−20°C
Application	The effect of non-ionic detergent on liposomes was studied with giant POPC liposomes. Increasing concentrations of detergent cause tubular protrusions, then indentations, to develop on spherical liposomes. At higher detergent concentrations, the liposomes burst.1

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

26853-31-6

MDL number

MFCD00043212

PubChem substance

24898382

Beilstein registry

4173237

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine used for?

2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine is primarily used in biochemical research for cell membrane studies, liposome and nanodisc formulation, and investigating glycerophospholipid metabolism.

What are the CAS number and chemical formula for this compound?

The CAS number for 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine is 26853-31-6, and its molecular formula is C42H82NO8P.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this compound with an assay of ≥99.0% (TLC). We do not represent this product as USP, BP, or EP grade.

What are the safety and handling recommendations for 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine?

Handling requires personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound is classified under WGK Germany 3.

How is this chemical typically shipped and exported?

This chemical is stored at -20°C and is available for global export by Tech Serve Solutions, a specialist supplier since 1998.

How can I request a sample or quote for 2-Oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine?

Please contact Tech Serve Solutions directly via our website or sales department to request a sample or a detailed quotation for your specific requirements.