2-O-Methyl-α-D-N-acetylneuraminic acid
2-O-Methyl-α-D-N-acetylneuraminic acid (CAS: 50930-22-8; Formula: C12H21NO9; Molar Mass: 323.30 g/mol) is a specialised carbohydrate derivative. It serves as a valuable model compound in biochemical research, particularly for investigating interactions with biological entities. Its applications include studying the binding affinities of viral hemagglutinins and metal ions, making it a useful reagent for glycobiology and virology research.
- IUPAC
- α-D-Neu-5-Ac-2→OCH3

Influenza Virus Hemagglutinin Binding Studies
This compound acts as a model to investigate the binding interactions of influenza virus hemagglutinin, a key protein involved in viral entry into host cells. Understanding these interactions is crucial for developing antiviral strategies.
Metal Ion Interaction Studies
2-O-Methyl-α-D-N-acetylneuraminic acid is employed as a model compound to study its interactions with various metal ions. This research can provide insights into the roles of metal ions in biological processes involving sialic acids.
Rotavirus and Toxin Binding Research
Related N-acetylneuraminic acid derivatives have been used to study the inhibition of rotavirus strains and the binding specificity of toxins like botulinum C16S toxin. This suggests potential utility in research concerning these pathogens.
| Molecular weight | 323.30 |
|---|---|
| Empirical formula | C12H21NO9 |
| Assay | ~95% (TLC) |
| Storage temperature | −20°C |
| Application | 2-O-Methyl-α-D-N-acetylneuraminic acid is a model compound for studies assessing the binding of influenza virus hemagglutinin1 and metal ions.2 N-acetylneuraminic acid has been used in a study to assess lactose-based sialylmimetics inhibition of the rhesus and human rotavirus strains. 3 It has also been used in a study to investigate the binding specificity of botulinum C16S toxin HA1 to various sugars. 4 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-O-Methyl-α-D-N-acetylneuraminic acid used for?
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It is used as a model compound for studies assessing the binding of influenza virus hemagglutinin and metal ions. It may also be relevant in research for understanding viral and toxin interactions with carbohydrates.
What is the CAS number and chemical formula for 2-O-Methyl-α-D-N-acetylneuraminic acid?
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The CAS number is 50930-22-8 and the empirical formula is C12H21NO9.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of approximately 95% as determined by TLC. We do not represent this product as USP, BP, EP or other pharmacopoeia grades.
How should 2-O-Methyl-α-D-N-acetylneuraminic acid be stored?
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It should be stored at -20°C.
What are the hazards associated with 2-O-Methyl-α-D-N-acetylneuraminic acid?
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The product has a WGK (German environmental hazard class) of 3, indicating it is hazardous to water. Appropriate handling procedures should be followed to avoid environmental release.
How is this chemical shipped?
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Tech Serve Solutions exports fine chemicals globally. Specific shipping and packaging details for 2-O-Methyl-α-D-N-acetylneuraminic acid can be provided upon request.
How can I request a sample or quote?
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Please contact our sales team to request a sample or obtain a quotation for 2-O-Methyl-α-D-N-acetylneuraminic acid.
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