2-Methylpyridine
2-Methylpyridine (CAS: 109-06-8), with the molecular formula C6H7N and a molecular weight of 93.13 g/mol, is a vital heterocyclic organic compound. Also known as 2-picoline, it serves as a foundational building block in chemical synthesis and is extensively used in the production of pharmaceuticals, agrochemicals, and dyes. Its reactive nature and pyridine ring structure make it a versatile intermediate for various organic transformations.
- IUPAC
- α-Picoline,2-Methylpyridine,2-Picoline,NSC 3409
- Synonyms
- α-Picoline2-PicolinePyridine, 2-methyl-NSC 3409
Chemical Synthesis Intermediate
2-Methylpyridine is a key building block in organic synthesis, particularly for creating more complex heterocyclic compounds. Its primary amine group and methyl substituent offer multiple reaction sites for derivatization.
Pharmaceutical Production
It functions as an intermediate in the synthesis of various active pharmaceutical ingredients (APIs). Its pyridine moiety is a common structural feature in many drug molecules.
Agrochemical Synthesis
2-Methylpyridine is employed in the manufacture of certain pesticides and herbicides, contributing to crop protection solutions.
Dye Manufacturing
This compound is utilised in the synthesis of specific dyes and pigments, leveraging its aromatic heterocyclic structure for colourant properties.
Research and Development
It is used in laboratory settings to study reaction mechanisms and develop new synthetic methodologies, as seen in studies involving electron and proton transfer reactions.
| Molecular weight | 93.13 |
|---|---|
| Empirical formula | C6H7N |
| Assay | 98% |
| Boiling point | 128-129 °C(lit.) |
| Density | 0.943 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.500(lit.) |
| Solubility | H2O: freely solublealcohol: misciblediethyl ether: miscible |
| Melting point | −70 °C(lit.) |
| Vapour pressure | 10 mmHg (24.4 °C) |
| Vapour density | 3.2 (vs air) |
| Autoignition temp | 995 °F |
| Application | 2-Picoline (2-Methylpyridine) was used to study the electron and proton transfer reactions of lumiflavin using Fourier transform ion cyclotron resonance mass spectrometry1. |
Hazard statements
- H226Flammable liquid and vapour
- H302Harmful if swallowed
- H311Toxic in contact with skin
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P312Call a POISON CENTER if you feel unwell
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 29 °C / 84.2 °F |
| Transport (UN / ADR) | UN 2313 3 / PGIII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | T |
| Risk statements (R) | 10-20/22-24-36/37 |
| Safety statements (S) | 26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methylpyridine used for?
+
2-Methylpyridine (2-Picoline) is used as a building block in chemical synthesis, particularly for pharmaceuticals, agrochemicals, and dyes. It is also employed in research and development to study reaction mechanisms.
What is the CAS number and formula for 2-Methylpyridine?
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The CAS number for 2-Methylpyridine is 109-06-8, and its chemical formula is C6H7N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methylpyridine with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Methylpyridine be handled safely?
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2-Methylpyridine is a flammable liquid and vapour (H226), harmful if swallowed or inhaled (H302+H332), and toxic in contact with skin (H311). It also causes serious eye irritation (H319) and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Avoid heat, sparks, and open flames. Seek immediate medical attention if exposed.
How is 2-Methylpyridine packed and shipped?
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2-Methylpyridine is shipped as a UN 2313, Class 3, Packing Group III hazardous material, requiring specific packaging and labelling for transport. Tech Serve Solutions adheres to all international shipping regulations.
How can I request a quote or sample for 2-Methylpyridine?
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To request a quote or sample of 2-Methylpyridine, please contact our sales team through the website or by phone. Provide your specific requirements, and we will assist you promptly.
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