Diazoxide

CAS 364-98-7C8H7ClN2O2SCell Biology

Diazoxide (CAS: 364-98-7; Formula: C8H7ClN2O2S) is a potent potassium channel opener with a molecular weight of 230.67 g/mol. This compound is recognised for its vasodilatory properties and is employed in scientific research, particularly in studies concerning ion channel modulation and cell signalling pathways. Available from Tech Serve Solutions, Diazoxide serves as a valuable reagent for biochemical and pharmacological investigations.

IUPAC: 7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide

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Diazoxide (C8H7ClN2O2S) — chemical structure, CAS 364-98-7; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesCell BiologyD-DIFIon ChannelsMonovalent Ion ChannelsPotassium Channel ModulatorsSchering PloughTeva

01 /Applications

Ion Channel Research

Diazoxide acts as a selective opener of ATP-sensitive potassium (KATP) channels. It is widely used in research to investigate the physiological and pathological roles of these channels in various tissues, including smooth muscle and pancreatic beta-cells.

Cardiovascular Studies

Due to its potent vasodilatory effects, Diazoxide is utilised in preclinical research to explore mechanisms of blood pressure regulation and to study conditions related to vascular smooth muscle function.

Pharmacological Tool

As a well-characterised bioactive small molecule, Diazoxide serves as a critical tool for probing cellular processes influenced by potassium channel activity and for evaluating potential therapeutic targets.

02 /Properties

Molecular weight	230.67
Empirical formula	C8H7ClN2O2S
Solubility	0.1 M NaOH: solubleH2O: insolublemethanol: soluble

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	22-36/37/38
Safety statements (S)	22-26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

364-98-7

MDL number

MFCD00078578

PubChem substance

24277831

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Diazoxide used for?

Diazoxide is primarily used as a research chemical for studying potassium channels, its vasodilatory effects, and related cellular signalling pathways. It is a valuable tool in ion channel research and cardiovascular studies.

What are the CAS number and formula for Diazoxide?

The CAS number for Diazoxide is 364-98-7, and its empirical formula is C8H7ClN2O2S.

What grade and purity does Tech Serve Solutions supply for Diazoxide?

Tech Serve Solutions supplies Diazoxide. The specific grade and purity are available upon request or via product specification sheets. TSS does not represent this product as USP, BP, or EP grade unless explicitly stated.

How should Diazoxide be handled safely?

Diazoxide is classified as harmful if swallowed and causes skin and eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling instructions.