2-Methylpyridine borane complex solution
2-Methylpyridine borane complex solution (CAS: 3999-38-0, Formula: C6H7N · BH3) is a stable, versatile reducing agent. With a molecular weight of 106.96, it is a key reagent in organic synthesis. Its applications include environmentally benign reductions, reductive amination, and N-alkylation of amino acid derivatives. This compound offers a safer and more manageable alternative to other borane sources in various chemical transformations.
- IUPAC
- 2-Picoline borane complex

Environmentally Benign Reducing Agent
2-Methylpyridine borane complex solution serves as an environmentally conscious choice for reduction reactions in organic synthesis, offering a favourable safety profile compared to some traditional reducing agents.
Reductive Amination
This complex is a valuable reactant for carrying out reductive amination, a crucial transformation for the synthesis of amines from carbonyl compounds and ammonia or primary/secondary amines.
N-Alkylation of Amino Acid Derivatives
It is employed in the N-benzyl protection of amino acid derivatives through reductive alkylation, a method essential for peptide synthesis and other complex organic structures.
Reductive Alkoxyamination
The reagent is applicable in reductive alkoxyamination, facilitating the formation of carbon-nitrogen and carbon-oxygen bonds in a single synthetic step.
| Molecular weight | 106.96 |
|---|---|
| Linear formula | C6H7N · BH3 |
| Assay | 95% |
| Storage temperature | 2-8°C |
| Application | • Environmentally benign reducing agent1Reactant for:• Reductive amination2• N-Benzyl-protection of amino acid derivatives by reductive alkylation3• Reductive alkoxyamination4 |
| Melting point | 44-46 °C(lit.) |


Hazard statements
- H261In contact with water releases flammable gas
- H351Suspected of causing cancer
Precautionary statements
- P231Handle under inert gas
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
- P422
| Flash point | 67 °C / 152.6 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 14/15-40 |
| Safety statements (S) | 36/37-43 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methylpyridine borane complex solution used for?
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It is used as an environmentally benign reducing agent and a reactant for reductive amination, N-alkylation of amino acid derivatives, and reductive alkoxyamination.
What are the CAS number and formula for 2-Methylpyridine borane complex solution?
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The CAS number is 3999-38-0 and the chemical formula is C6H7N · BH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methylpyridine borane complex solution with an assay of 95%. We do not represent this product as USP, BP, or EP grade.
How should 2-Methylpyridine borane complex solution be handled and stored?
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Due to its flammability and potential health hazards (H261, H351), handle with appropriate personal protective equipment in a well-ventilated area. Store at 2-8°C as indicated by safety data. Precautions include P231 + P232, P261, P305 + P351 + P338, and P422.
Is 2-Methylpyridine borane complex solution a controlled substance?
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The provided data does not indicate that 2-Methylpyridine borane complex solution is a controlled substance.
How can I request a quote or sample?
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Please contact our sales team directly via our website or by phone to request a quote or sample of 2-Methylpyridine borane complex solution.
How is 2-Methylpyridine borane complex solution packed and exported?
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Tech Serve Solutions professionally packs and exports chemicals globally, ensuring compliance with all relevant shipping regulations for hazardous materials.
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