2-Methylbutyryl chloride
2-Methylbutyryl chloride (CAS 57526-28-0) is an organic compound with the linear formula C2H5CH(CH3)COCl and a molecular weight of 120.58 g/mol. As an acid halide and carbonyl compound, it serves as a versatile building block in chemical synthesis. Its primary applications lie in organic chemistry for introducing the 2-methylbutyryl group into various molecules, facilitating the creation of more complex organic structures for research and development purposes.

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of complex organic molecules. It facilitates the introduction of the 2-methylbutyryl moiety through acylation reactions.
Pharmaceutical Building Block
Serves as a structural component in the development of novel pharmaceutical compounds. Its reactivity allows for versatile derivatization in drug discovery.
Agrochemical Development
Employed in the synthesis of active ingredients for agrochemical applications. It contributes to the creation of new pesticides and herbicides.
Material Science Research
Can be used in the preparation of specialised polymers and materials. Its functional group allows for incorporation into polymer backbones or side chains.
| Molecular weight | 120.58 |
|---|---|
| Linear formula | C2H5CH(CH3)COCl |
| Assay | 97% |
| Boiling point | 117-121 °C(lit.) |
| Density | 0.972 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.418(lit.) |


Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 20 °C / 68 °F |
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methylbutyryl chloride used for?
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2-Methylbutyryl chloride is primarily used as a building block in organic synthesis, particularly in the pharmaceutical and agrochemical industries, for introducing the 2-methylbutyryl group into target molecules.
What is the CAS number and chemical formula for 2-Methylbutyryl chloride?
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The CAS number for 2-Methylbutyryl chloride is 57526-28-0, and its linear formula is C2H5CH(CH3)COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methylbutyryl chloride with a minimum assay of 97%. This product is suitable for research and general chemical synthesis. TSS does not represent this product as USP, EP, or BP grade.
How should 2-Methylbutyryl chloride be handled safely?
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2-Methylbutyryl chloride is a highly flammable liquid and vapour (H225) and causes severe skin burns and eye damage (H314). Handle with extreme caution in a well-ventilated area, using appropriate personal protective equipment including face shield, gloves, goggles, and a suitable respirator. Keep away from heat and open flames.
Is 2-Methylbutyryl chloride shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Methylbutyryl chloride, and can facilitate international shipments.
How can I obtain a quote or sample of 2-Methylbutyryl chloride?
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To request a quote or a sample of 2-Methylbutyryl chloride, please visit the Tech Serve Solutions website or contact our sales department directly.
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