2-Methyl-6-nitrobenzonitrile
2-Methyl-6-nitrobenzonitrile (CAS: 1885-76-3) is an organic compound with the formula O2NC6H3(CH3)CN and a molecular weight of 162.15 g/mol. This chemical serves as a valuable building block in organic synthesis. It is primarily utilised in the preparation of more complex molecules, finding applications in the development of pharmaceutical intermediates and other fine chemicals. Its specific structure makes it useful for introducing nitro and nitrile functionalities into target compounds.
- IUPAC
- 6-Nitro-o-tolunitrile
- Synonyms
- 6-Nitro-o-tolunitrile
Synthesis of Quinazoline Derivatives
2-Methyl-6-nitrobenzonitrile has been employed in the synthesis of 5-arylthiomethyl-2,4-diaminoquinazolines, contributing to the development of novel heterocyclic compounds.
Preparation of Isoquinolinones
This compound acts as a starting reagent in microwave-assisted synthetic routes, notably for the preparation of 8-amino-2-methyl-3,4-dihydroisoquinolin-1-one.
General Organic Synthesis Building Block
As a functionalised benzonitrile, it is a versatile intermediate for introducing specific chemical moieties in multi-step organic synthesis pathways.
| Molecular weight | 162.15 |
|---|---|
| Linear formula | O2NC6H3(CH3)CN |
| Assay | 98% |
| Application | 2-Methyl-6-nitrobenzonitrile was used in the synthesis of 5-arylthiomethyl-2,4-diaminoquinazolines1. It was also used as starting reagent in the microwave assisted synthesis of 8-amino-2-methyl-3,4-dihydroisoquinolin-1-one2. |
| Melting point | 108-110 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methyl-6-nitrobenzonitrile used for?
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2-Methyl-6-nitrobenzonitrile is primarily used as a building block in organic synthesis, particularly for creating heterocyclic compounds such as quinazoline derivatives and isoquinolinones.
What is the CAS number and molecular formula for 2-Methyl-6-nitrobenzonitrile?
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The CAS number for 2-Methyl-6-nitrobenzonitrile is 1885-76-3, and its molecular formula is O2NC6H3(CH3)CN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methyl-6-nitrobenzonitrile with a minimum purity of 98%. We do not represent this product as USP, BP, or EP grade.
How should 2-Methyl-6-nitrobenzonitrile be handled safely?
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2-Methyl-6-nitrobenzonitrile is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation. It is recommended to use a dust mask (N95 US type), eyeshields, and gloves, and to handle it in a well-ventilated area.
Is 2-Methyl-6-nitrobenzonitrile a controlled substance?
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Based on the provided data, 2-Methyl-6-nitrobenzonitrile is not listed as a controlled substance.
How is 2-Methyl-6-nitrobenzonitrile supplied and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Methyl-6-nitrobenzonitrile, adhering to international shipping regulations.
How can I request a sample or quote for 2-Methyl-6-nitrobenzonitrile?
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To request a sample or quote for 2-Methyl-6-nitrobenzonitrile, please contact the Tech Serve Solutions sales team through our website or by phone.
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