2-Methyl-6-nitrobenzoic anhydride
2-Methyl-6-nitrobenzoic anhydride (CAS: 434935-69-0) is an organic compound with the molecular formula C16H12N2O7 and a molecular weight of 344.28 g/mol. This chemical serves as a valuable lactonization reagent, primarily utilised in synthetic organic chemistry for the preparation of diverse macrolide natural products and other complex organic molecules. Its anhydride structure facilitates its reactivity in various synthetic transformations.
- IUPAC
- MNBA
Macrolide Natural Product Synthesis
2-Methyl-6-nitrobenzoic anhydride is employed as a key reagent in the synthesis of macrolide natural products. Its utility lies in promoting lactonization reactions, a critical step in assembling these complex molecular architectures.
Organic Synthesis Building Block
As a carboxylic acid anhydride, this compound functions as a versatile building block in organic synthesis. It can be incorporated into various reaction schemes to introduce specific functional groups or to facilitate cyclisation processes.
Reagent for Lactonization
The compound's primary application is as a lactonization reagent. It enables the efficient formation of cyclic ester (lactone) moieties, which are prevalent in many biologically active molecules and natural products.
| Molecular weight | 344.28 |
|---|---|
| Empirical formula | C16H12N2O7 |
| Assay | 97% |
| Application | A versatile lactonization reagent used in the preparation of a variety of macrolide natural products.1 |
| Melting point | 173-177 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methyl-6-nitrobenzoic anhydride used for?
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2-Methyl-6-nitrobenzoic anhydride is primarily used as a lactonization reagent in organic synthesis, particularly for the preparation of macrolide natural products.
What are the CAS number and formula for 2-Methyl-6-nitrobenzoic anhydride?
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The CAS number for 2-Methyl-6-nitrobenzoic anhydride is 434935-69-0, and its molecular formula is C16H12N2O7.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methyl-6-nitrobenzoic anhydride with a minimum purity of 97% (Assay). This product is not represented as meeting USP, BP, EP, or other pharmacopoeia standards.
How should 2-Methyl-6-nitrobenzoic anhydride be handled?
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2-Methyl-6-nitrobenzoic anhydride is a Warning chemical that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust.
Is 2-Methyl-6-nitrobenzoic anhydride available for export?
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Yes, Tech Serve Solutions, established in 1998, is a specialist global supplier and exporter of fine chemicals, including 2-Methyl-6-nitrobenzoic anhydride.
How can I request a quote or sample for 2-Methyl-6-nitrobenzoic anhydride?
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To request a quote or a sample of 2-Methyl-6-nitrobenzoic anhydride, please contact our sales team through the website or via direct inquiry.
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