2-Methyl-5-nitrophenol
2-Methyl-5-nitrophenol (CAS: 5428-54-6, Formula: C7H7NO3, Molar Mass: 153.14 g/mol) is a substituted phenol and an organic building block. This compound, also known as 5-Nitro-o-cresol, is valuable in chemical synthesis due to its reactive hydroxyl and nitro groups. It serves as an intermediate in the production of dyes, pharmaceuticals, and other speciality chemicals, making it a key component in various industrial and research applications.
- IUPAC
- 5-Nitro-o-cresol
- Synonyms
- 5-Nitro-o-cresol

Chemical Synthesis Intermediate
2-Methyl-5-nitrophenol is used as a precursor in the synthesis of more complex organic molecules. Its functional groups allow for diverse chemical transformations, making it valuable in multi-step synthetic routes.
Dye and Pigment Production
The nitro and phenol functionalities of this compound lend themselves to applications in the colourant industry. It can be incorporated into the synthesis of certain azo dyes and other chromophores.
Pharmaceutical Research
As an organic building block, 2-Methyl-5-nitrophenol may be employed in the early stages of pharmaceutical research and development. It can serve as a starting material for the creation of novel drug candidates.
| Molecular weight | 153.14 |
|---|---|
| Linear formula | CH3C6H3(NO2)OH |
| Assay | 98% |
| Melting point | 111-115 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2446 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methyl-5-nitrophenol used for?
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2-Methyl-5-nitrophenol is primarily used as an intermediate in chemical synthesis, including the production of dyes and potentially in pharmaceutical research. It is a valuable organic building block.
What are the CAS number and formula for 2-Methyl-5-nitrophenol?
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The CAS number for 2-Methyl-5-nitrophenol is 5428-54-6, and its chemical formula is C7H7NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methyl-5-nitrophenol with an assay of 98%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Methyl-5-nitrophenol be handled safely?
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2-Methyl-5-nitrophenol is classified as a Warning substance, indicated by GHS07. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area.
Is 2-Methyl-5-nitrophenol a controlled substance?
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Based on the provided data, there is no indication that 2-Methyl-5-nitrophenol is a controlled substance.
How is 2-Methyl-5-nitrophenol packed, shipped, and exported?
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2-Methyl-5-nitrophenol is packed and shipped according to standard chemical industry practices, complying with regulations for hazardous materials, including UN 2446, Class 6.1, Packing Group III. Tech Serve Solutions exports globally.
How can I request a sample or a quote for 2-Methyl-5-nitrophenol?
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To request a sample or a quote for 2-Methyl-5-nitrophenol, please contact the Tech Serve Solutions sales team through our website or by phone, providing your specific requirements.
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