2-Methoxy-5-methylaniline
2-Methoxy-5-methylaniline (CAS: 120-71-8), with the chemical formula CH3OC6H3(CH3)NH2 and a molecular weight of 137.18 g/mol, is a valuable organic building block. This aromatic amine serves as a key intermediate in chemical synthesis, particularly in the production of dyes and in analytical chemistry research. Tech Serve Solutions supplies this compound for various laboratory and industrial applications, adhering to strict quality standards.
- IUPAC
- 5-Methyl-o-anisidine,6-Methoxy-m-toluidine,p-Cresidine
- Synonyms
- 5-Methyl-o-anisidine6-Methoxy-m-toluidinep-Cresidine

Synthesis of Azo Dyes
2-Methoxy-5-methylaniline is employed in the synthesis of complex organic molecules, such as 4-(4-Amino-5-methoxy-2-methylphenylazo)-5-hydroxy-naphthalene-2,7-disulfonic acid, highlighting its utility in dye chemistry.
Analytical Chemistry Applications
This compound has been utilised in studies involving polymeric ionic liquids as sorbent coatings for the selective extraction of genotoxic impurities and structurally alerting compounds from various matrices.
Method Development for Aromatic Amine Detection
It has been used in research to develop sensitive analytical methods, such as high-performance liquid chromatography coupled with electrochemical detection, for determining aromatic amines in commercial hair dyes.
| Molecular weight | 137.18 |
|---|---|
| Linear formula | CH3OC6H3(CH3)NH2 |
| Assay | 99% |
| Boiling point | 235 °C(lit.) |
| Vapour density | 4.7 (vs air) |
| Application | 2-Methoxy-5-methylaniline was used in the synthesis of 4-(4-Amino-5-methoxy-2-methylphenylazo)-5-hydroxy-naphthalene-2,7-disulfonic acid1. 2-Methoxy-5-methylaniline was used to analyse the application of polymeric ionic liquids as selective solid-phase microextraction sorbent coatings for the analysis of genotoxic impurities and structurally alerting compounds such as alkyl halides and aromatics2. 2-Methoxy-5-methylaniline was used in a study to develop a sensitive analytical method for the determination of aromatic amines found in commercial hair dyes using high liquid chromatography coupled to an electrochemical detector by using the ionic liquid 1-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide in the mobile phase3. |
| Melting point | 50-52 °C(lit.) |


Hazard statements
- H302Harmful if swallowed
- H319Causes serious eye irritation
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P305IF IN EYES
- P308IF exposed or concerned
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-22 |
| Safety statements (S) | 53-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methoxy-5-methylaniline used for?
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2-Methoxy-5-methylaniline is primarily used as a chemical intermediate in the synthesis of dyes and in analytical chemistry research for method development.
What is the CAS number and chemical formula for 2-Methoxy-5-methylaniline?
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The CAS number is 120-71-8, and the chemical formula is CH3OC6H3(CH3)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methoxy-5-methylaniline with a purity of 99%. This product is suitable for research and general chemical synthesis; TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling precautions for 2-Methoxy-5-methylaniline?
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2-Methoxy-5-methylaniline is classified as dangerous, with Danger as the signal word. It carries hazard statements H302 (Harmful if swallowed), H319 (Causes serious eye irritation), and H350 (May cause cancer). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, must be used. Handle in a well-ventilated area and avoid exposure. Consult the Safety Data Sheet for comprehensive guidance.
Does Tech Serve Solutions export 2-Methoxy-5-methylaniline?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Methoxy-5-methylaniline.
How can I request a sample or quote for 2-Methoxy-5-methylaniline?
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Please contact our sales team via the website or direct email to request a sample or a quotation for 2-Methoxy-5-methylaniline.
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