2-Methoxy-4-nitrophenyl isocyanate
2-Methoxy-4-nitrophenyl isocyanate (CAS: 33484-67-2; Formula: CH3OC6H3(NO2)NCO; MW: 194.14) is a nitro-substituted aromatic isocyanate. It serves as a valuable building block in organic synthesis. Its reactivity is characteristic of isocyanates, readily participating in addition reactions with nucleophiles. This compound is primarily utilised in the chemical synthesis of complex organic molecules and as an intermediate in the development of new chemical entities.

Organic Synthesis Intermediate
Used as a key intermediate in the synthesis of various organic compounds. The isocyanate group enables facile reaction with amines, alcohols, and other nucleophiles to form ureas, carbamates, and other derivatives.
Building Block for Heterocycles
Can be employed in the construction of nitrogen-containing heterocyclic ring systems. Its functional groups allow for cyclisation reactions leading to diverse molecular architectures.
Pharmaceutical Research
Serves as a reagent in the discovery and development of potential pharmaceutical agents. It can be incorporated into structures being investigated for biological activity.
| Molecular weight | 194.14 |
|---|---|
| Linear formula | CH3OC6H3(NO2)NCO |
| Assay | 97% |
| Melting point | 113-116 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3335 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methoxy-4-nitrophenyl isocyanate used for?
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2-Methoxy-4-nitrophenyl isocyanate is primarily used as a building block in organic synthesis and as an intermediate in the preparation of various organic compounds, including potential pharmaceutical agents and heterocyclic structures.
What are the CAS number and formula for 2-Methoxy-4-nitrophenyl isocyanate?
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The CAS number is 33484-67-2, and the molecular formula is CH3OC6H3(NO2)NCO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methoxy-4-nitrophenyl isocyanate with a purity of 97%. We do not represent this product as USP, BP, or EP grade.
What are the main hazards associated with 2-Methoxy-4-nitrophenyl isocyanate?
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This compound is classified with GHS07 and the signal word 'Warning'. It is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and eye irritation, and respiratory irritation (H302-H312-H315-H319-H332-H335). Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, should be used.
How is 2-Methoxy-4-nitrophenyl isocyanate packed, shipped, and exported?
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2-Methoxy-4-nitrophenyl isocyanate is carefully packed according to international shipping regulations and is available for global export by Tech Serve Solutions.
How can I request a sample or a quote for 2-Methoxy-4-nitrophenyl isocyanate?
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You can request a sample or a quote by contacting our sales department through the website or by calling us directly. Please specify the quantity required.
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