2-Mercapto-1-methylimidazole
2-Mercapto-1-methylimidazole (CAS: 60-56-0), with the molecular formula C4H6N2S and a molecular weight of 114.17 g/mol, is a key heterocyclic compound. It functions as a valuable building block in chemical synthesis and finds application in cell biology research. This imidazole derivative is supplied by TSS with an assay of ≥99%, suitable for research and chemical synthesis purposes.
- IUPAC
- 1-Methyl-2-imidazolethiol,2-Mercapto-1-methylimidazole,Methimazole
- Synonyms
- 1-Methyl-2-imidazolethiolMethimazole

Chromatography Ligand
2-Mercapto-1-methylimidazole has been utilised as a hydrophobic charge-induction chromatography ligand for the purification of antibodies, demonstrating its utility in bioseparation processes.
Ionic Liquid Synthesis
This compound served as a precursor in the preparation of novel nitrile-functionalized methimazole-based room temperature ionic liquids, expanding the scope of ionic liquid chemistry.
Chemical Synthesis Building Block
As a versatile building block, 2-Mercapto-1-methylimidazole is employed in various organic synthesis pathways for the construction of complex molecules.
| Molecular weight | 114.17 |
|---|---|
| Empirical formula | C4H6N2S |
| Assay | ≥99% |
| Application | 2-Mercapto-1-methylimidazole was employed as hydrophobic charge-induction chromatography ligand for antibody purification.1 It was also used in preparation of nitrile functionalized methimazole-based room temperature ionic liquids.2 |
| Melting point | 144-147 °C(lit.) |


Hazard statements
- H317May cause an allergic skin reaction
- H361Suspected of damaging fertility or the unborn child
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 63-43-62 |
| Safety statements (S) | 26-27-36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CYP1A2(1544) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Mercapto-1-methylimidazole used for?
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2-Mercapto-1-methylimidazole is used as a hydrophobic charge-induction chromatography ligand for antibody purification and in the preparation of nitrile-functionalized room temperature ionic liquids. It also serves as a building block in chemical synthesis and is studied in cell biology.
What are the CAS number and formula for 2-Mercapto-1-methylimidazole?
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The CAS number for 2-Mercapto-1-methylimidazole is 60-56-0, and its empirical formula is C4H6N2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Mercapto-1-methylimidazole with a purity of ≥99%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 2-Mercapto-1-methylimidazole be handled safely?
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2-Mercapto-1-methylimidazole is a Warning substance with hazard statements H317 (May cause an allergic skin reaction) and H361 (Suspected of damaging fertility or the unborn child). Handle with appropriate personal protective equipment including eyeshields, gloves, and respiratory protection (e.g., N100 respirator cartridges). Ensure good ventilation.
Is 2-Mercapto-1-methylimidazole a controlled substance?
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The provided data does not indicate that 2-Mercapto-1-methylimidazole is a controlled substance.
How is 2-Mercapto-1-methylimidazole packed, shipped, and exported?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging and shipping methods compliant with international regulations for chemical products like 2-Mercapto-1-methylimidazole.
How can I request a sample or quote for 2-Mercapto-1-methylimidazole?
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To request a sample or a quote for 2-Mercapto-1-methylimidazole, please contact our sales department through the TSS website or by phone.
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