2-Ketobutyric acid
2-Ketobutyric acid (CAS: 600-18-0) is a vital organic building block with the linear formula CH3CH2COCOOH and a molecular weight of 102.09 g/mol. As an alpha-keto acid, it plays a role in metabolic pathways and serves as a versatile intermediate in chemical synthesis. This compound is valued for its reactivity, making it a useful precursor in the creation of more complex molecules within pharmaceutical and research settings.
- IUPAC
- α-Ketobutyric acid,Propionylformic acid
- Synonyms
- α-Ketobutyric acidPropionylformic acid

Organic Synthesis Intermediate
2-Ketobutyric acid is employed as a key intermediate in the synthesis of various organic compounds. Its keto and carboxylic acid functionalities allow for diverse chemical transformations, facilitating the construction of complex molecular architectures.
Biochemical Research
This compound is utilised in biochemical studies, particularly in research related to intermediary metabolism. Its structural similarity to natural alpha-keto acids makes it valuable for investigating enzymatic reactions and metabolic pathways.
Pharmaceutical Precursor
As a building block, 2-Ketobutyric acid can serve as a precursor in the development of pharmaceutical agents. Its incorporation into synthetic routes aids in the creation of novel drug candidates and active pharmaceutical ingredients.
| Molecular weight | 102.09 |
|---|---|
| Linear formula | CH3CH2COCOOH |
| Assay | 97% |
| Boiling point | 84 °C/20 mmHg(lit.) |
| Solubility | H2O: soluble0.1 g/mL, clear |
| Storage temperature | 2-8°C |
| Melting point | 30-34 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Ketobutyric acid used for?
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2-Ketobutyric acid is primarily used as an intermediate in organic synthesis and for biochemical research, including its role as a precursor in the development of pharmaceutical agents.
What is the CAS number and formula for 2-Ketobutyric acid?
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The CAS number for 2-Ketobutyric acid is 600-18-0, and its linear formula is CH3CH2COCOOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Ketobutyric acid with a purity of 97%. We do not represent this product as USP, BP, or EP grade; it is supplied for laboratory and research purposes.
How should 2-Ketobutyric acid be handled safely?
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2-Ketobutyric acid is classified with warning signal word and carries hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields and gloves, should be used. Consult the Safety Data Sheet for detailed handling and emergency procedures.
How is 2-Ketobutyric acid packed and shipped?
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2-Ketobutyric acid is carefully packed according to industry standards for safe transport and is exported globally by Tech Serve Solutions.
How can I request a sample or quote for 2-Ketobutyric acid?
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To request a sample or a quotation for 2-Ketobutyric acid, please contact our sales department through the website or by phone.
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