2-Hydroxychalcone
2-Hydroxychalcone (CAS 42224-53-3) is an organic compound with a molecular weight of 224.25 g/mol, presenting as a ketone. It is a valuable building block and intermediate in chemical synthesis. Its structure lends itself to applications in the development of more complex molecules within research and industrial settings, particularly in organic chemistry and materials science.

Organic Synthesis Intermediate
2-Hydroxychalcone serves as a key intermediate in the synthesis of various organic compounds. Its reactive functional groups allow for further chemical modifications, enabling the construction of complex molecular architectures.
Research and Development
This compound is utilized in research laboratories for exploring novel chemical reactions and developing new synthetic methodologies. It is a useful reagent for academic and industrial R&D projects.
Building Block for Specialty Chemicals
As a versatile building block, 2-Hydroxychalcone contributes to the creation of specialty chemicals with specific properties for diverse applications, including potential uses in materials science.
| Molecular weight | 224.25 |
|---|---|
| Linear formula | HOC6H4CH=CHCOC6H5 |
| Assay | 95% |
| Melting point | 144-150 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Hydroxychalcone used for?
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2-Hydroxychalcone is primarily used as an intermediate and building block in organic synthesis and for research and development purposes.
What are the CAS number and molecular formula for 2-Hydroxychalcone?
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The CAS number for 2-Hydroxychalcone is 42224-53-3. Its linear formula is HOC₆H₄CH=CHCOC₆H₅, and its molecular weight is 224.25.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Hydroxychalcone with an assay of 95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Hydroxychalcone be handled safely?
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Handle 2-Hydroxychalcone with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. It is a Warning compound, with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335).
How is 2-Hydroxychalcone packed, shipped, and exported?
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Tech Serve Solutions expertly packs, ships, and exports 2-Hydroxychalcone globally, adhering to all necessary regulatory and safety standards for chemical transport.
How can I request a sample or a quote for 2-Hydroxychalcone?
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To request a sample or a quote for 2-Hydroxychalcone, please contact our sales team through the website or via direct inquiry.
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