2′-Hydroxy-5′-methyl-3′-nitroacetophenone
2′-Hydroxy-5′-methyl-3′-nitroacetophenone (CAS 66108-30-3) is a chemical compound with the linear formula HOC₆H₂(CH₃)(NO₂)COCH₃ and a molecular weight of 195.17 g/mol. This nitroacetophenone derivative functions as a versatile building block in organic synthesis. It is primarily utilised in chemical research and the development of more complex molecules, particularly within the realm of organic chemistry and materials science.

Organic Synthesis Intermediate
This compound serves as a key intermediate in the synthesis of diverse organic molecules. Its functional groups allow for various chemical transformations, making it valuable in multi-step synthetic pathways.
Research and Development
Utilised in academic and industrial research laboratories for the exploration of novel chemical reactions and the creation of new compounds. Its structure makes it a useful starting material for medicinal chemistry and materials science research.
Fine Chemical Building Block
As a substituted acetophenone, it acts as a foundational building block for constructing more elaborate chemical structures. It is supplied for use in various chemical synthesis applications.
| Molecular weight | 195.17 |
|---|---|
| Linear formula | HOC6H2(CH3)(NO2)COCH3 |
| Assay | 99% |
| Melting point | 133-136 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-Hydroxy-5′-methyl-3′-nitroacetophenone used for?
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2′-Hydroxy-5′-methyl-3′-nitroacetophenone (CAS 66108-30-3) is primarily used as a building block and intermediate in organic synthesis and chemical research.
What is the CAS number and molecular formula for this product?
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The CAS number for 2′-Hydroxy-5′-methyl-3′-nitroacetophenone is 66108-30-3. The linear formula is HOC₆H₂(CH₃)(NO₂)COCH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2′-Hydroxy-5′-methyl-3′-nitroacetophenone with a purity of 99% (Assay). This product is not classified as USP, BP, EP, or pharmacopoeia grade.
How should 2′-Hydroxy-5′-methyl-3′-nitroacetophenone be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Avoid breathing dust. Ensure adequate ventilation. Refer to the Safety Data Sheet for comprehensive handling information. It is classified as a Warning, with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335).
Is this chemical a controlled substance?
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Based on the provided data, 2′-Hydroxy-5′-methyl-3′-nitroacetophenone (CAS 66108-30-3) is not indicated as a controlled substance.
How is this product packed and exported?
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Tech Serve Solutions packs and exports chemicals in compliance with international shipping regulations. Specific packaging details are available upon request for bulk or custom orders.
How can I request a quote or sample?
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To request a quote or sample of 2′-Hydroxy-5′-methyl-3′-nitroacetophenone, please contact our sales team via the website or by phone, providing your specific requirements and shipping details.
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