Ciproxifan maleate
Ciproxifan maleate (CAS: 184025-19-2), with the empirical formula C16H18N2O2 · C4H4O4 and a molecular weight of 386.40 g/mol, is a white to beige powder. This compound is recognised as a potent histamine H3 receptor antagonist. It serves as a valuable tool in research settings, particularly for investigating neurological pathways and developing potential therapeutic agents targeting conditions modulated by histamine signalling.
- IUPAC
- Cyclopropyl (4-[3-(1H-imidazol-4-yl)propyloxy]phenyl) ketone maleate salt,FUB 359 maleate salt
- Synonyms
- FUB 359 maleate saltCyclopropyl (4-[3-(1H-imidazol-4-yl)propyloxy]phenyl) ketone maleate salt
Histamine H3 Receptor Antagonism Research
Ciproxifan maleate is widely used as a selective histamine H3 receptor antagonist. It allows researchers to probe the physiological roles of the H3 receptor in the central nervous system and periphery.
Neuroscience and Neurotransmission Studies
This compound is instrumental in studying neurotransmission processes, particularly those involving histamine. Its application aids in understanding the regulation of various neuronal functions and the development of treatments for neurological disorders.
GPCR Modulator in Drug Discovery
As a G protein-coupled receptor (GPCR) modulator, Ciproxifan maleate is employed in drug discovery programs. It assists in the identification and validation of new therapeutic targets for a range of conditions.
| Molecular weight | 386.40 |
|---|---|
| Empirical formula | C16H18N2O2 · C4H4O4 |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | DMSO: soluble32 mg/mLH2O: insoluble |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-43 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ciproxifan maleate used for?
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Ciproxifan maleate is primarily used as a research tool, specifically as a selective histamine H3 receptor antagonist, aiding in studies of neuroscience, neurotransmission, and drug discovery involving GPCRs.
What is the CAS number and formula for Ciproxifan maleate?
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The CAS number for Ciproxifan maleate is 184025-19-2, and its empirical formula is C16H18N2O2 · C4H4O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ciproxifan maleate with a minimum purity of ≥98% (HPLC). This product is supplied for research and laboratory use, and is not represented as USP, BP, EP, or other pharmacopoeial grades.
How should Ciproxifan maleate be handled safely?
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Handle Ciproxifan maleate with appropriate personal protective equipment, including a dust mask (N95 US standard), eyeshields, faceshields, and gloves. It is a Warning substance, classified with hazards H302 (Harmful if swallowed), H315 (Causes skin irritation), H317 (May cause an allergic skin reaction), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation).
How is Ciproxifan maleate packed and shipped?
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Ciproxifan maleate is typically supplied as a powder and is carefully packed for domestic and international shipment, adhering to all relevant regulations for chemical export.
How can I request a sample or quote for Ciproxifan maleate?
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To request a sample or a quote for Ciproxifan maleate, please contact our sales team through the website or by phone. Please provide your specific requirements and shipping details.
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