2-Fluoropyridine-4-carboxaldehyde
2-Fluoropyridine-4-carboxaldehyde (CAS: 131747-69-8; C6H4FNO) is a fluorinated heterocyclic aldehyde with a molecular weight of 125.10 g/mol. This compound serves as a valuable building block in organic synthesis, particularly for the construction of complex molecules containing pyridine rings. It is frequently employed in the development of novel pharmaceuticals and agrochemicals due to the unique electronic and steric properties imparted by the fluorine atom and aldehyde functionality.
- IUPAC
- 2-Fluoroisonicotinaldehyde

Organic Synthesis Intermediate
Utilised as a versatile intermediate in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. The aldehyde group readily participates in condensation, oxidation, and reduction reactions, while the fluoropyridine core can be further functionalised.
Pharmaceutical Research
A key building block for medicinal chemistry programmes. Its structure allows for incorporation into drug candidates targeting a range of therapeutic areas, leveraging the metabolic stability and binding affinity often associated with fluorinated heterocycles.
Agrochemical Development
Contributes to the synthesis of new pesticides and herbicides. The fluoropyridine moiety can enhance biological activity and alter the environmental persistence of active ingredients.
Materials Science
May be employed in the development of functional materials, such as organic semiconductors or ligands for coordination chemistry, where its electronic properties can be exploited.
| Molecular weight | 125.10 |
|---|---|
| Empirical formula | C6H4FNO |
| Assay | 97% |
| Boiling point | 357-403 °C (decomposition) |
| Density | 1.257 g/mL at 25 °C |
| Refractive index | n20/D 1.512 |
| Storage temperature | −20°C |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Flash point | 86 °C / 186.8 °F |
|---|---|
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoropyridine-4-carboxaldehyde used for?
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2-Fluoropyridine-4-carboxaldehyde is primarily used as an intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It functions as a building block for creating more complex molecules containing fluorinated pyridine structures.
What are the CAS number and formula for 2-Fluoropyridine-4-carboxaldehyde?
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The CAS number is 131747-69-8, and the empirical formula is C6H4FNO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoropyridine-4-carboxaldehyde with an assay of 97%. This is a technical grade suitable for research and synthesis purposes; it is not supplied as USP, BP, or EP grade.
How should 2-Fluoropyridine-4-carboxaldehyde be handled and stored?
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Handle 2-Fluoropyridine-4-carboxaldehyde with care. It is classified as harmful if swallowed (H302) and causes skin (H315) and serious eye irritation (H319). Wear protective gloves, eye protection, and face protection. Store in a cool, dry place at -20°C, tightly sealed.
Is 2-Fluoropyridine-4-carboxaldehyde a controlled substance?
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Based on the provided data, 2-Fluoropyridine-4-carboxaldehyde is not indicated as a controlled substance.
How is this chemical packed and exported?
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2-Fluoropyridine-4-carboxaldehyde is packaged according to industry standards for chemical reagents and intermediates. Tech Serve Solutions is experienced in exporting fine chemicals globally.
How can I request a quote or sample?
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To request a quote or a sample of 2-Fluoropyridine-4-carboxaldehyde, please contact our sales team through the website or by phone. Details are available on the Tech Serve Solutions contact page.
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