2-Fluoro-6-iodobenzoyl chloride
2-Fluoro-6-iodobenzoyl chloride (CAS: 111771-12-1) is a fluorinated organic compound with the linear formula FC<sub>6</sub>H<sub>3</sub>(I)COCl and a molecular weight of 284.45 g/mol. This reactive acid halide serves as a valuable building block in organic synthesis, particularly for introducing the 2-fluoro-6-iodobenzoyl moiety into more complex molecules. It finds utility in the development of pharmaceuticals and advanced materials.
Organic Synthesis Intermediate
This compound acts as a key intermediate in multi-step organic syntheses. Its reactive acyl chloride group readily participates in acylation reactions, forming esters, amides, and other carbonyl derivatives.
Pharmaceutical Research
2-Fluoro-6-iodobenzoyl chloride is employed in the synthesis of novel pharmaceutical candidates. The presence of both fluorine and iodine atoms can influence the pharmacokinetic and pharmacodynamic properties of target drug molecules.
Materials Science
The unique structural features of this molecule make it useful in the creation of specialised polymers and functional materials where specific electronic or physical properties are desired.
| Molecular weight | 284.45 |
|---|---|
| Linear formula | FC6H3(I)COCl |
| Assay | 97% |
| Density | 1.956 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5910(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Fluoro-6-iodobenzoyl chloride used for?
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2-Fluoro-6-iodobenzoyl chloride is primarily used as a building block and intermediate in organic synthesis, particularly in the development of pharmaceuticals and advanced materials.
What is the CAS number and molecular formula for 2-Fluoro-6-iodobenzoyl chloride?
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The CAS number is 111771-12-1, and the linear molecular formula is FC<sub>6</sub>H<sub>3</sub>(I)COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Fluoro-6-iodobenzoyl chloride with a minimum assay of 97%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated.
How should 2-Fluoro-6-iodobenzoyl chloride be handled?
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2-Fluoro-6-iodobenzoyl chloride is classified as Danger with hazard statement H314 (Causes severe skin burns and eye damage). It requires full protective equipment including gloves, goggles, a face shield, and appropriate respiratory protection. Handle in a well-ventilated area.
How is 2-Fluoro-6-iodobenzoyl chloride packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports chemicals in compliance with international regulations for hazardous materials. This compound is shipped under UN 3265, Class 8, Packing Group II.
How can I request a sample or quote for 2-Fluoro-6-iodobenzoyl chloride?
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To request a sample or a formal quotation, please contact our sales department via the website or direct email, providing your specific requirements.
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