2-Chloro-5-(difluoromethyl)pyridine
2-Chloro-5-(difluoromethyl)pyridine (CAS: 71701-99-0) is a fluorinated pyridine derivative with the molecular formula C6H4ClF2N and a molecular weight of 163.55 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its unique difluoromethyl and pyridine moieties offer specific reactivity for constructing complex molecular architectures.

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs), leveraging its fluorinated pyridine structure for targeted drug discovery and development.
Agrochemical Synthesis
A key building block for creating novel pesticides, herbicides, and fungicides, contributing to crop protection and agricultural innovation.
Material Science
Incorporated into the design of advanced materials where its specific chemical properties can impart desired characteristics.
Organic Synthesis Reagent
Serves as a versatile reagent in complex organic transformations and the synthesis of diverse chemical compounds.
| Molecular weight | 163.55 |
|---|---|
| Empirical formula | C6H4ClF2N |
| Assay | 97% |
| Density | 1.368 g/mL at 25 °C |
| Refractive index | n20/D 1.492 |
| Storage temperature | 2-8°C |

Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Flash point | 107 °C / 224.6 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-5-(difluoromethyl)pyridine used for?
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2-Chloro-5-(difluoromethyl)pyridine (CAS: 71701-99-0) is primarily used as a building block in organic synthesis, notably for the development of pharmaceuticals and agrochemicals.
What is the CAS number and formula for 2-Chloro-5-(difluoromethyl)pyridine?
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The CAS number for 2-Chloro-5-(difluoromethyl)pyridine is 71701-99-0, and its empirical formula is C6H4ClF2N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-5-(difluoromethyl)pyridine with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should 2-Chloro-5-(difluoromethyl)pyridine be handled safely?
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2-Chloro-5-(difluoromethyl)pyridine is classified as a Warning with hazard statement H319 (Causes serious eye irritation). Handle with appropriate personal protective equipment, including eye protection, and follow precautionary statement P305 + P351 + P338 (IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing).
How is 2-Chloro-5-(difluoromethyl)pyridine packed, shipped, and exported?
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2-Chloro-5-(difluoromethyl)pyridine is packed according to industry standards for chemical safety and stability. Tech Serve Solutions expertly handles global shipping and export of this compound.
How can I request a sample or quote for 2-Chloro-5-(difluoromethyl)pyridine?
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To request a sample or quote for 2-Chloro-5-(difluoromethyl)pyridine, please contact our sales team through the website or direct inquiry channels.
What is the storage temperature for this chemical?
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2-Chloro-5-(difluoromethyl)pyridine should be stored at temperatures between 2-8°C.
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