2-Chloro-4-methoxypyridine
2-Chloro-4-methoxypyridine (CAS: 17228-69-2), a halogenated pyridine derivative with the molecular formula C6H6ClNO and a molecular weight of 143.57 g/mol, is a valuable chemical intermediate. It serves as a key building block in organic synthesis, particularly for constructing more complex heterocyclic compounds. Its applications span various research and development sectors, contributing to the creation of novel molecules with potential utility in pharmaceuticals and materials science.

Organic Synthesis Intermediate
2-Chloro-4-methoxypyridine is widely utilised as a versatile intermediate in the synthesis of complex organic molecules. Its reactive chlorine atom and pyridine core allow for diverse functionalisation pathways in multi-step synthetic routes.
Pharmaceutical Research
This compound serves as a structural motif or precursor in the development of new pharmaceutical agents. Its incorporation into potential drug candidates leverages the established biological activity of pyridine derivatives.
Heterocyclic Chemistry
As a halogenated heterocyclic building block, it is instrumental in the construction of novel heterocyclic systems. Researchers employ it to explore new chemical entities with tailored properties.
| Molecular weight | 143.57 |
|---|---|
| Empirical formula | C6H6ClNO |
| Assay | 97% |
| Boiling point | 224-225 °C(lit.) |
| Density | 1.258 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5400(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-4-methoxypyridine used for?
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2-Chloro-4-methoxypyridine is primarily used as a building block and intermediate in organic synthesis, particularly for the creation of complex heterocyclic compounds relevant to pharmaceutical research and development.
What is the CAS number and chemical formula for 2-Chloro-4-methoxypyridine?
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The CAS number for 2-Chloro-4-methoxypyridine is 17228-69-2, and its empirical formula is C6H6ClNO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-4-methoxypyridine with a minimum assay of 97%. This is a technical/research grade, and TSS does not represent it as USP, BP, or EP.
How should 2-Chloro-4-methoxypyridine be handled?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator (e.g., type ABEK EN14387 filter). It is classified as a warning substance (GHS07) and may cause skin (H315), eye (H319), and respiratory tract irritation (H335).
Is 2-Chloro-4-methoxypyridine a controlled substance?
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Based on the provided data, there is no indication that 2-Chloro-4-methoxypyridine is a controlled substance. However, customers should verify local regulations.
How is 2-Chloro-4-methoxypyridine packed and exported?
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2-Chloro-4-methoxypyridine is carefully packed according to industry standards to ensure safe transit and is available for global export by Tech Serve Solutions.
How can I request a quote or sample?
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To request a quote or sample of 2-Chloro-4-methoxypyridine, please contact our sales team through the website or by phone, providing your contact details and required quantity.
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