2-Chloro-4-methoxybenzyl bromide
2-Chloro-4-methoxybenzyl bromide (CAS 54788-17-9) is a halogenated hydrocarbon with a molecular weight of 235.51 g/mol. As an organic building block and aryl compound, it plays a crucial role in chemical synthesis. This compound is primarily utilised in research and development laboratories for the creation of more complex organic molecules. Its reactive benzyl bromide functionality makes it a versatile intermediate for various synthetic pathways.
- IUPAC
- 1-(Bromomethyl)-2-chloro-4-methoxybenzene
- Synonyms
- 1-(Bromomethyl)-2-chloro-4-methoxybenzene

Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of complex organic molecules due to its reactive benzyl bromide and methoxy-substituted aryl functionalities. It is valuable in constructing carbon-carbon and carbon-heteroatom bonds in pharmaceutical and agrochemical research.
Building Block for Heterocycles
The compound can be employed in the preparation of various heterocyclic structures, which are prevalent motifs in many biologically active compounds. Its structural features allow for diverse cyclisation reactions.
Reagent in Medicinal Chemistry
Utilised by medicinal chemists as a starting material or intermediate for the development of novel drug candidates. Its reactivity facilitates the introduction of the 2-chloro-4-methoxybenzyl moiety into potential therapeutic agents.
| Molecular weight | 235.51 |
|---|---|
| Empirical formula | C8H8BrClO |
| Assay | 97% |
| Storage temperature | −20°C |
| Melting point | 53-57 °C |


Hazard statements
- H301Toxic if swallowed
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | 104 °C / 219.2 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-4-methoxybenzyl bromide used for?
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2-Chloro-4-methoxybenzyl bromide (CAS 54788-17-9) is primarily used as a building block and intermediate in organic synthesis and medicinal chemistry research. It is valuable for constructing complex organic molecules and heterocyclic structures.
What is the CAS number and molecular formula for 2-Chloro-4-methoxybenzyl bromide?
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The CAS number for 2-Chloro-4-methoxybenzyl bromide is 54788-17-9. Its empirical formula (Hill notation) is C8H8BrClO, with a molecular weight of 235.51 g/mol.
What grade and purity does Tech Serve Solutions supply for 2-Chloro-4-methoxybenzyl bromide?
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Tech Serve Solutions supplies 2-Chloro-4-methoxybenzyl bromide with a minimum assay of 97%. We do not represent this product as USP, BP, or EP grade; it is suitable for research and laboratory applications.
What are the safety considerations when handling 2-Chloro-4-methoxybenzyl bromide?
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2-Chloro-4-methoxybenzyl bromide is classified as Danger with hazards including H301 (Toxic if swallowed), H314 (Causes severe skin burns and eye damage), and H335 (May cause respiratory irritation). Handle with extreme care, wearing appropriate personal protective equipment (gloves, eye protection, respiratory protection) in a well-ventilated area. Avoid ingestion, skin contact, and inhalation. Refer to the Safety Data Sheet (SDS) for full details.
How is 2-Chloro-4-methoxybenzyl bromide packed, shipped, and exported?
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2-Chloro-4-methoxybenzyl bromide is carefully packed to ensure safe transit. Tech Serve Solutions, established in 1998, has extensive experience in exporting fine chemicals globally. Contact us for specific shipping and export inquiries.
How can I request a sample or a quote for 2-Chloro-4-methoxybenzyl bromide?
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To request a sample or a quote for 2-Chloro-4-methoxybenzyl bromide, please contact our sales team through the website or by phone. Provide your specific requirements for prompt assistance.
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