2-Chloro-3-(trifluoromethyl)phenol
2-Chloro-3-(trifluoromethyl)phenol (CAS: 138377-34-1) is a halogenated aromatic organic compound with the molecular formula ClC6H3(CF3)OH and a molecular weight of 196.55 g/mol. This phenol derivative is primarily used as a building block in organic synthesis and chemical research. Its distinct chemical structure, featuring both chlorine and trifluoromethyl substituents on a phenolic ring, makes it valuable for introducing specific functionalities into more complex molecules.

Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of various organic compounds. Its reactive hydroxyl group and the presence of electron-withdrawing substituents allow for diverse chemical transformations.
Pharmaceutical Research
Utilised in the research and development of new pharmaceutical agents. The trifluoromethyl group is a common feature in many drug molecules, influencing lipophilicity and metabolic stability.
Agrochemical Development
Can be employed as a building block for the creation of novel agrochemicals. The combination of halogen and trifluoromethyl groups can impart specific biological activities.
Material Science
Potentially used in the synthesis of specialized polymers or functional materials where its unique structural features are advantageous.
| Molecular weight | 196.55 |
|---|---|
| Linear formula | ClC6H3(CF3)OH |
| Assay | 98% |
| Boiling point | 160 °C(lit.) |
| Density | 1.479 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.482(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 79 °C / 174.2 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-3-(trifluoromethyl)phenol used for?
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2-Chloro-3-(trifluoromethyl)phenol (CAS: 138377-34-1) is primarily used as a building block in organic synthesis and chemical research, particularly in the development of pharmaceuticals and agrochemicals.
What is the CAS number and chemical formula for 2-Chloro-3-(trifluoromethyl)phenol?
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The CAS number is 138377-34-1 and the chemical formula is ClC6H3(CF3)OH.
What grade and purity does Tech Serve Solutions supply for 2-Chloro-3-(trifluoromethyl)phenol?
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Tech Serve Solutions supplies 2-Chloro-3-(trifluoromethyl)phenol with a minimum assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 2-Chloro-3-(trifluoromethyl)phenol be handled safely?
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This compound is classified as a Warning with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It requires appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection. Handle in a well-ventilated area.
Is 2-Chloro-3-(trifluoromethyl)phenol shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Chloro-3-(trifluoromethyl)phenol.
How can I request a quote or sample for 2-Chloro-3-(trifluoromethyl)phenol?
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To request a quote or sample, please contact our sales department via the website or listed phone number, providing your specific requirements.
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