2-Chloro-3-pyridinecarboxaldehyde
2-Chloro-3-pyridinecarboxaldehyde (CAS: 36404-88-3) is a key organic building block with the molecular formula C6H4ClNO and a molecular weight of 141.56 g/mol. This halogenated pyridine derivative serves as a valuable intermediate in the synthesis of various heterocyclic compounds. It is particularly noted for its role as a starting material in the preparation of 5-azaindoles through the Hemetsberger-Knittel reaction. Available from Tech Serve Solutions with an assay of 97%.
- IUPAC
- Chloro-2-formyl-3-pyridine
- Synonyms
- Chloro-2-formyl-3-pyridine
Synthesis of 5-Azaindoles
Utilised as a precursor in the Hemetsberger-Knittel reaction for the synthesis of 5-azaindoles. This involves the thermal decomposition of alkenyl azides derived from this compound.
Heterocyclic Chemistry Intermediate
Serves as a versatile building block in organic synthesis, particularly for creating complex heterocyclic structures containing a pyridine core.
Fine Chemical Synthesis
A useful reagent in the development and production of fine chemicals and pharmaceutical intermediates, leveraging its reactive aldehyde and chloro-pyridine functionalities.
| Molecular weight | 141.56 |
|---|---|
| Empirical formula | C6H4ClNO |
| Assay | 97% |
| Application | Starting material for the preparation of 5-azaindoles by the Hemetsberger-Knittel reaction involving the thermal decomposition of alkenyl azides.1 |
| Melting point | 50-54 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-3-pyridinecarboxaldehyde used for?
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2-Chloro-3-pyridinecarboxaldehyde (CAS: 36404-88-3) is primarily used as a starting material for the synthesis of 5-azaindoles via the Hemetsberger-Knittel reaction and as a general building block in organic and heterocyclic chemistry.
What are the CAS number and formula for 2-Chloro-3-pyridinecarboxaldehyde?
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The CAS number is 36404-88-3 and the empirical formula is C6H4ClNO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Chloro-3-pyridinecarboxaldehyde with an assay of 97%. This product is intended for research and chemical synthesis purposes and is not represented as USP, BP, EP, or pharmaceutical grade.
How should 2-Chloro-3-pyridinecarboxaldehyde be handled safely?
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Based on its GHS classification, 2-Chloro-3-pyridinecarboxaldehyde is harmful if swallowed (H302), may cause an allergic skin reaction (H317), and causes serious eye irritation (H319). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shields, and gloves, should be used. Handle in a well-ventilated area.
Is 2-Chloro-3-pyridinecarboxaldehyde available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Chloro-3-pyridinecarboxaldehyde, serving customers worldwide.
How can I request a quote or sample for 2-Chloro-3-pyridinecarboxaldehyde?
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Please contact our sales team via the website or direct email to request a quote or sample for 2-Chloro-3-pyridinecarboxaldehyde.
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