2-Bromo-6-fluorophenylboronic acid
2-Bromo-6-fluorophenylboronic acid (CAS: 913835-80-0) is an organoboron compound with the chemical formula BrC6H3(F)B(OH)2 and a molecular weight of 218.82 g/mol. It serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions like Suzuki-Miyaura coupling. This disubstituted aryl boronic acid is a key intermediate for the development of complex molecules in pharmaceuticals and materials science research.
Suzuki-Miyaura Cross-Coupling Reagent
2-Bromo-6-fluorophenylboronic acid is extensively employed as a coupling partner in Suzuki-Miyaura reactions. This allows for the formation of new carbon-carbon bonds, essential for synthesising complex biaryl compounds used in medicinal chemistry and advanced materials.
Pharmaceutical Intermediate
This compound acts as a crucial intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its specific substitution pattern is often leveraged to introduce fluorinated and brominated phenyl motifs into drug candidates.
Organic Synthesis Building Block
Beyond specific coupling reactions, 2-Bromo-6-fluorophenylboronic acid functions as a versatile building block in general organic synthesis. It enables the precise introduction of a 2-bromo-6-fluorophenyl moiety into diverse molecular architectures.
Materials Science Research
The unique electronic and structural properties imparted by the bromo and fluoro substituents make this boronic acid useful in the design and synthesis of novel organic materials for applications in electronics or optoelectronics.
| Molecular weight | 218.82 |
|---|---|
| Linear formula | BrC6H3(F)B(OH)2 |
| Melting point | 138-143 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-6-fluorophenylboronic acid used for?
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2-Bromo-6-fluorophenylboronic acid is primarily used as a valuable building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for creating carbon-carbon bonds. It is a key intermediate in the development of pharmaceuticals and advanced materials.
What are the CAS number and chemical formula for 2-Bromo-6-fluorophenylboronic acid?
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The CAS number for 2-Bromo-6-fluorophenylboronic acid is 913835-80-0, and its chemical formula is BrC6H3(F)B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-6-fluorophenylboronic acid as a reagent for research and development purposes. Specific assay information and available grades can be obtained by requesting a quote or contacting our sales team. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for 2-Bromo-6-fluorophenylboronic acid?
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2-Bromo-6-fluorophenylboronic acid requires careful handling. Protective equipment such as eyeshields and gloves should be worn. In environments with potential for airborne dust, use a type N95 (US) or type P1 (EN143) respirator filter. Consult the Safety Data Sheet (SDS) for comprehensive handling and hazard information.
How is 2-Bromo-6-fluorophenylboronic acid packed and shipped?
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Tech Serve Solutions ensures appropriate packaging for all chemicals, adhering to international shipping regulations. Specific packaging details are available upon request. We export globally to meet the needs of researchers and manufacturers worldwide.
How can I request a sample or quote for 2-Bromo-6-fluorophenylboronic acid?
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To request a sample or a quote for 2-Bromo-6-fluorophenylboronic acid, please visit the product page on our website and use the designated request forms, or contact our sales department directly via email or phone.
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