2-Bromo-5-hydroxypyrazine
2-Bromo-5-hydroxypyrazine (CAS: 374063-92-0) is a heterocyclic organic compound with the molecular formula C4H3BrN2O and a molecular weight of 174.98 g/mol. This brominated pyrazine derivative serves as a valuable building block in chemical synthesis, particularly for the development of complex molecules within pharmaceutical and materials science research. Its structure lends itself to various derivatisation reactions, making it a useful intermediate for novel compound discovery.

Pharmaceutical Intermediate
Utilised as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates. Its pyrazine core and reactive bromine atom facilitate the construction of diverse molecular scaffolds for medicinal chemistry programmes.
Organic Synthesis Building Block
A versatile building block for constructing more complex heterocyclic systems. The presence of both a bromine atom and a hydroxyl group allows for regioselective functionalisation and further elaboration in multi-step synthetic routes.
Materials Science Research
Can be employed in the development of novel organic materials, such as dyes, polymers, or electronic components, where its specific electronic and structural properties can be exploited.
| Molecular weight | 174.98 |
|---|---|
| Empirical formula | C4H3BrN2O |
| Assay | 95% |
| Melting point | 115-119 °C |


Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Water hazard class (WGK, DE) | 1 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-5-hydroxypyrazine used for?
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2-Bromo-5-hydroxypyrazine is primarily used as a building block in organic synthesis and as an intermediate in the development of pharmaceuticals and novel materials.
What are the CAS number and molecular formula for 2-Bromo-5-hydroxypyrazine?
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The CAS number is 374063-92-0 and the molecular formula is C4H3BrN2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-5-hydroxypyrazine with an assay of 95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 2-Bromo-5-hydroxypyrazine be handled?
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2-Bromo-5-hydroxypyrazine is classified as Dangerous. It is harmful if swallowed (H302) and causes serious eye damage (H318). Appropriate personal protective equipment, including eye protection (P280, P305+P351+P338), should be worn during handling. Ensure good ventilation.
Is 2-Bromo-5-hydroxypyrazine a controlled substance?
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The provided data does not indicate that 2-Bromo-5-hydroxypyrazine is a controlled substance.
How is 2-Bromo-5-hydroxypyrazine packed and shipped?
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Tech Serve Solutions packages and exports 2-Bromo-5-hydroxypyrazine according to international shipping regulations for hazardous chemicals. Specific packaging details are available upon request.
How can I request a quote or sample for 2-Bromo-5-hydroxypyrazine?
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To request a quote or sample, please contact our sales department via the website or by phone, providing your contact details and the product CAS number 374063-92-0.
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