2-Bromo-4-chloropyridine
2-Bromo-4-chloropyridine (CAS: 22918-01-0) is a halogenated pyridine derivative with the molecular formula C5H3BrClN and a molecular weight of 192.44 g/mol. This compound serves as a versatile building block in organic synthesis, particularly within the pharmaceutical and agrochemical industries. Its utility stems from the reactive halogen substituents, enabling diverse coupling and substitution reactions for the construction of complex molecular architectures.

Pharmaceutical Intermediate
Utilised in the synthesis of active pharmaceutical ingredients (APIs) where the pyridine core and halogen functionalities are incorporated into target drug molecules. Its structure lends itself to the development of novel therapeutic agents.
Agrochemical Synthesis
Serves as a key intermediate in the development of pesticides, herbicides, and fungicides. The presence of bromine and chlorine atoms allows for targeted modifications to create compounds with specific biological activities.
Material Science Research
Can be employed in the creation of functional materials and organic electronic components. The electronic properties of the pyridine ring, modulated by halogen substituents, are of interest in this field.
Organic Synthesis Reagent
A valuable reagent for introducing a substituted pyridine moiety into organic molecules via various cross-coupling reactions, such as Suzuki or Stille couplings, facilitating the assembly of complex structures.
| Molecular weight | 192.44 |
|---|---|
| Empirical formula | C5H3BrClN |
| Assay | 95% |
| Storage temperature | −20°C |
| Melting point | 12-17 °C |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Bromo-4-chloropyridine used for?
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2-Bromo-4-chloropyridine (CAS: 22918-01-0) is primarily used as a building block in organic synthesis, especially for the creation of pharmaceutical intermediates and agrochemicals.
What is the CAS number and formula for 2-Bromo-4-chloropyridine?
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The CAS number is 22918-01-0, and the empirical formula (Hill notation) is C5H3BrClN.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Bromo-4-chloropyridine with a minimum assay of 95%. This product is suitable for research and chemical synthesis purposes. TSS does not represent this product as USP, BP, or EP grade.
How should 2-Bromo-4-chloropyridine be handled safely?
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2-Bromo-4-chloropyridine is classified as Danger with hazards including H302 (Harmful if swallowed), H315 (Causes skin irritation), H318 (Causes serious eye damage), and H335 (May cause respiratory irritation). Handle with appropriate personal protective equipment (gloves, eye protection, respiratory protection) in a well-ventilated area or fume hood. Avoid ingestion, skin contact, and inhalation.
How is 2-Bromo-4-chloropyridine shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Bromo-4-chloropyridine. We ensure compliant packaging and shipping procedures for international destinations.
How can I request a sample or quote for 2-Bromo-4-chloropyridine?
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To request a sample or obtain a quote for 2-Bromo-4-chloropyridine, please use the 'Request a Quote' or 'Sample Request' form on our website, or contact our sales department directly.
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