2-Benzyloxyethyl chloroformate
2-Benzyloxyethyl chloroformate (CAS: 56456-19-0) is an organic compound with the linear formula ClCO2CH2CH2OCH2C6H5 and a molecular weight of 214.65 g/mol. As an acid halide and carbonyl compound, it serves as a valuable building block in organic synthesis. It is primarily utilised in the chemical industry for the introduction of the benzyloxyethoxycarbonyl protecting group in various chemical reactions.
Protecting Group Chemistry
This chloroformate derivative is employed to introduce the benzyloxyethoxycarbonyl (ZOC) protecting group onto amines and alcohols. This group is stable under various reaction conditions and can be selectively removed when needed.
Organic Synthesis Intermediate
As a versatile building block, 2-Benzyloxyethyl chloroformate facilitates the construction of more complex organic molecules. Its reactive chloroformate moiety allows for straightforward derivatisation.
Research and Development
It is used in laboratory settings for the development of new synthetic routes and the exploration of novel chemical compounds in research institutions and pharmaceutical companies.
| Molecular weight | 214.65 |
|---|---|
| Linear formula | ClCO2CH2CH2OCH2C6H5 |
| Assay | 97% |
| Density | 1.19 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.508(lit.) |
| Vapour pressure | 1.36 mmHg (20 °C) |
| Storage temperature | 2-8°C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Benzyloxyethyl chloroformate used for?
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2-Benzyloxyethyl chloroformate is used as a building block in organic synthesis, primarily for introducing the benzyloxyethoxycarbonyl (ZOC) protecting group onto amines and alcohols.
What is the CAS number and formula for 2-Benzyloxyethyl chloroformate?
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The CAS number is 56456-19-0 and the linear formula is ClCO2CH2CH2OCH2C6H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Benzyloxyethyl chloroformate with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2-Benzyloxyethyl chloroformate be handled safely?
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2-Benzyloxyethyl chloroformate is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Handling requires full-face protection, gloves, goggles, and appropriate respiratory protection such as a multi-purpose combination respirator cartridge or type ABEK filter.
How is this chemical packed, shipped, and exported?
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Products are carefully packed according to international shipping regulations. Tech Serve Solutions has extensive experience in exporting fine chemicals globally.
How can I request a quote or sample?
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Please contact our sales team via the website or direct email to request a quotation or a sample for evaluation.
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