2-Aminomethyl-1,4-benzodioxane
2-Aminomethyl-1,4-benzodioxane (CAS: 4442-59-5) is an organic compound with the molecular formula C9H11NO2. It serves as a valuable building block in chemical synthesis, particularly within the realm of heterocyclic chemistry. Its structure, featuring a benzodioxane core with an aminomethyl substituent, makes it a versatile intermediate for the development of more complex molecules.
- IUPAC
- (2,3-Dihydrobenzo-1,4-dioxin-2-yl)methylamine,1,4-Benzodioxane-2-methylamine,2,3-Dihydro-1,4-benzodioxin-2-methanamine
- Synonyms
- (2,3-Dihydrobenzo-1,4-dioxin-2-yl)methylamine1,4-Benzodioxane-2-methylamine2,3-Dihydro-1,4-benzodioxin-2-methanamine

Chemical Synthesis Intermediate
This compound is utilised as a key intermediate in the synthesis of various organic molecules. Its functional groups allow for diverse chemical transformations, making it useful in multi-step synthetic routes.
Heterocyclic Compound Development
As a heterocyclic building block, 2-Aminomethyl-1,4-benzodioxane is employed in the construction of complex heterocyclic structures. These structures are often of interest in pharmaceutical research and materials science.
Research and Development
It is frequently used in research laboratories for exploring new chemical reactions and developing novel compounds. Its availability supports academic and industrial R&D efforts.
| Molecular weight | 165.19 |
|---|---|
| Empirical formula | C9H11NO2 |
| Assay | 97% |
| Boiling point | 105-110 °C/3 mmHg |
| Density | 1.1679 g/mL at 25 °C |
| Refractive index | n20/D 1.5594 |


Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Aminomethyl-1,4-benzodioxane used for?
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2-Aminomethyl-1,4-benzodioxane is primarily used as a building block and intermediate in organic synthesis, particularly for creating heterocyclic compounds and in research and development activities.
What are the CAS number and molecular formula for 2-Aminomethyl-1,4-benzodioxane?
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The CAS number for 2-Aminomethyl-1,4-benzodioxane is 4442-59-5, and its molecular formula is C9H11NO2. Its molecular weight is 165.19 g/mol.
What grade and purity does Tech Serve Solutions supply for 2-Aminomethyl-1,4-benzodioxane?
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Tech Serve Solutions supplies 2-Aminomethyl-1,4-benzodioxane with an assay of 97%. This product is not represented as USP, BP, or EP grade.
How should 2-Aminomethyl-1,4-benzodioxane be handled safely?
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Handle with care. This compound is classified as Danger, causing skin irritation (H315), serious eye damage (H318), and may cause respiratory irritation (H335). Use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, and ensure adequate ventilation. Refer to the safety data sheet for detailed handling instructions.
Is 2-Aminomethyl-1,4-benzodioxane a controlled substance?
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Based on the provided data, there is no indication that 2-Aminomethyl-1,4-benzodioxane is a controlled substance.
How is 2-Aminomethyl-1,4-benzodioxane packed and shipped?
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Tech Serve Solutions can provide information on packing and shipping upon request, adhering to all necessary regulations for chemical export.
How can I request a quote or sample of 2-Aminomethyl-1,4-benzodioxane?
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Please contact our sales department directly through our website or by phone to request a quote or sample of 2-Aminomethyl-1,4-benzodioxane.
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