2-Aminoisobutyric acid

CAS 62-57-7(CH3)2C(NH2)COOHChemical Synthesis

2-Aminoisobutyric acid (CAS: 62-57-7) is a non-proteinogenic amino acid with the molecular formula (CH3)2C(NH2)COOH. It is a derivative of alanine, featuring two methyl groups on the alpha-carbon. This unique structure contributes to its role as a building block in chemical synthesis and peptide chemistry, particularly in the creation of unnatural peptides and peptidomimetics.

IUPAC: α-Aminoisobutyric acid,2-Methylalanine,Aib
Synonyms: 2-MethylalanineAibα-Aminoisobutyric acid

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2-Aminoisobutyric acid ((CH3)2C(NH2)COOH) — chemical structure, CAS 62-57-7; Chemistry, fine chemical supplied by Tech Serve Solutions

Alanine DerivativesChemical BiologyChemical SynthesisPeptide Chemistry

01 /Applications

Chemical Synthesis

2-Aminoisobutyric acid serves as a valuable chiral building block in organic synthesis. Its steric bulk and the presence of both amine and carboxylic acid functionalities allow for diverse derivatization and incorporation into complex molecular architectures.

Peptide Chemistry

As an unnatural amino acid, it is employed in the synthesis of peptides to introduce conformational constraints or to enhance stability against enzymatic degradation. This is crucial for developing peptide-based therapeutics and research tools.

Chemical Biology

In chemical biology, 2-Aminoisobutyric acid can be used to probe protein structure and function or to develop novel biomaterials. Its incorporation can alter peptide or protein folding patterns and binding affinities.

02 /Properties

Molecular weight	103.12
Linear formula	(CH3)2C(NH2)COOH
Assay	98%
Melting point	≥300 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3
Ignition residue	≤0.3%

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

62-57-7

MDL number

MFCD00008049

PubChem substance

24888304

Beilstein registry

506496

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Aminoisobutyric acid used for?

2-Aminoisobutyric acid is used in chemical synthesis, peptide chemistry, and chemical biology, often as a building block for unnatural peptides and peptidomimetics.

What is the CAS number and formula for 2-Aminoisobutyric acid?

The CAS number is 62-57-7 and the linear formula is (CH3)2C(NH2)COOH.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 2-Aminoisobutyric acid with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.

What are the safety and handling precautions for 2-Aminoisobutyric acid?

Handle 2-Aminoisobutyric acid with appropriate personal protective equipment, including eyeshields and gloves. A respirator filter of type N95 (US) or P1 (EN143) is recommended. Refer to the Safety Data Sheet for comprehensive handling information.

How is 2-Aminoisobutyric acid packed, shipped, and exported?

Tech Serve Solutions packs, ships, and exports 2-Aminoisobutyric acid in compliance with all relevant regulations to ensure safe and secure delivery worldwide.