2-Amino-5-nitrophenol
2-Amino-5-nitrophenol (CAS: 121-88-0), with the molecular formula H₂NC₆H₃(NO₂)OH and a molecular weight of 154.12 g/mol, is a valuable organic intermediate. This compound is primarily employed as a reactant in diazotization and coupling reactions. It also serves as a crucial building block in the synthesis of various biologically and pharmacologically active molecules. Supplied by Tech Serve Solutions, it is essential for chemical synthesis and organic chemistry research.
- IUPAC
- 2-Hydroxy-4-nitroaniline,3-Hydroxy-4-aminonitrobenzene,3-Nitro-6-aminophenol,5-Nitro-2-amino-1-hydroxybenzene,5-Nitro-2-aminophenol,NSC 7087
- Synonyms
- 2-Hydroxy-4-nitroaniline3-Hydroxy-4-aminonitrobenzene3-Nitro-6-aminophenol5-Nitro-2-amino-1-hydroxybenzene5-Nitro-2-aminophenolNSC 7087

Diazotization and Coupling Reactions
2-Amino-5-nitrophenol serves as a key reactant in diazotization processes, followed by coupling reactions. This enables the formation of azo compounds, which are foundational in dye chemistry and the synthesis of various organic materials.
Synthesis of Bioactive Molecules
This compound is utilised as a precursor in the preparation of diverse molecules possessing biological and pharmacological activity. Its structure lends itself to incorporation into complex organic frameworks for drug discovery and development.
Organic Building Block
As an organic building block, 2-Amino-5-nitrophenol is instrumental in constructing more complex chemical structures. Its functional groups allow for versatile transformations in multi-step synthetic routes within academic and industrial research.
| Molecular weight | 154.12 |
|---|---|
| Linear formula | H2NC6H3(NO2)OH |
| Application | Reactant for:• Diazotation and coupling reactions1• Preparation of biologically and pharmacologically active molecules2 |
| Melting point | 198-202 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-5-nitrophenol used for?
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2-Amino-5-nitrophenol is primarily used as a reactant in diazotization and coupling reactions, and in the preparation of biologically and pharmacologically active molecules.
What is the CAS number and molecular formula for 2-Amino-5-nitrophenol?
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The CAS number is 121-88-0 and the molecular formula is H₂NC₆H₃(NO₂)OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical. Please refer to the product specifications or contact us for detailed information regarding the assay and grade. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should 2-Amino-5-nitrophenol be handled?
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2-Amino-5-nitrophenol is a skin irritant, causes serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including Eyeshields, Gloves, and a dust mask type N95 (US). Ensure good ventilation and avoid breathing dust. Refer to the Safety Data Sheet (SDS) for comprehensive handling information.
How is 2-Amino-5-nitrophenol packed and shipped?
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2-Amino-5-nitrophenol is carefully packed to ensure its integrity during transit. As a global supplier and exporter, Tech Serve Solutions adheres to all relevant shipping regulations for chemical substances.
How can I request a sample or quote for 2-Amino-5-nitrophenol?
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To request a sample or a quote for 2-Amino-5-nitrophenol, please visit the Tech Serve Solutions website or contact our sales department directly.
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