2-Amino-5-nitrothiazole
2-Amino-5-nitrothiazole (CAS: 121-66-4, C3H3N3O2S) is a chemical compound with a molecular weight of 145.14. This substance primarily functions as a diazo component in the synthesis of monoazo disperse dyes and has been utilised as a matrix in mass spectrometry studies of oligonucleotides and proteins. It is supplied by TSS with an assay of 97% and is a key intermediate for various chemical synthesis applications.

Disperse Dye Synthesis
2-Amino-5-nitrothiazole serves as a diazo component in the production of monoazo disperse dyes, contributing to the colouration of textiles and other materials.
Mass Spectrometry Matrix
This compound has been employed as a matrix in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry, aiding in the analysis of oligonucleotides and proteins.
Heterocyclic Building Block
As a heterocyclic compound containing a thiazole ring, it is a valuable building block in organic synthesis for creating more complex molecular structures.
| Molecular weight | 145.14 |
|---|---|
| Empirical formula | C3H3N3O2S |
| Assay | 97% |
| Solubility | 95% ethanol: soluble1g/150g at 20 °Cdiethyl ether: soluble1g/250g at 20 °Cchloroform: insolublewater: slightly soluble |
| Application | 2-Amino-5-nitrothiazole was used as diazo component in the synthesis of monoazo disperse dyes1. It was used as matrix during matrix-assisted laser desorption/ionization time-of-flight mass spectrometric study of oligonucleotide and protein2. |
| Melting point | 195-200 °C (dec.)(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-5-nitrothiazole used for?
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2-Amino-5-nitrothiazole is primarily used as a diazo component in the synthesis of monoazo disperse dyes and as a matrix in mass spectrometry analysis of biomolecules like oligonucleotides and proteins.
What are the CAS number and formula for 2-Amino-5-nitrothiazole?
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The CAS number for 2-Amino-5-nitrothiazole is 121-66-4, and its molecular formula is C3H3N3O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Amino-5-nitrothiazole with an assay of 97%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should 2-Amino-5-nitrothiazole be handled safely?
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2-Amino-5-nitrothiazole is classified with GHS07 symbol and carries a Warning signal word. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Ensure adequate ventilation and avoid breathing dust.
Is 2-Amino-5-nitrothiazole available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2-Amino-5-nitrothiazole.
How can I request a sample or quote for 2-Amino-5-nitrothiazole?
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Please contact our sales team through the website or call us directly to request a sample or obtain a quote for 2-Amino-5-nitrothiazole.
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