(±)-2-Amino-4-phosphonobutyric acid
(±)-2-Amino-4-phosphonobutyric acid (CAS: 20263-07-4, Formula: C4H10NO5P) is a white solid with a molecular weight of 183.10 g/mol. As a phosphonic acid analogue of glutamate, it functions as an NMDA receptor antagonist. This compound is valuable in neuroscience research for studying excitatory amino acid pathways and neurotransmission, particularly within the central nervous system.
- IUPAC
- (±)-AP-4

Neuroscience Research
Serves as a tool for investigating NMDA receptor function and glutamate signaling pathways in the central nervous system. It aids in understanding excitatory amino acid neurotransmission and its role in various neurological processes.
Cell Signaling Studies
Utilised in cell biology to explore intracellular signaling cascades influenced by excitatory amino acids. It helps researchers elucidate the complex mechanisms of cell communication.
Ion Channel Modulation
Applied in research focused on ionotropic glutamate receptors and ligand-gated ion channels. Its antagonistic properties are instrumental in studying channel activity and regulation.
| Molecular weight | 183.10 |
|---|---|
| Empirical formula | C4H10NO5P |
| Form | solid |
| Colour | white |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRINA(2907)rat ... Grin2b(24410) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (±)-2-Amino-4-phosphonobutyric acid used for?
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(±)-2-Amino-4-phosphonobutyric acid is primarily used in neuroscience research to study NMDA receptor function, excitatory amino acid pathways, and neurotransmission. It is also employed in cell signaling and ion channel modulation studies.
What are the CAS number and formula for (±)-2-Amino-4-phosphonobutyric acid?
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The CAS number is 20263-07-4 and the molecular formula is C4H10NO5P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research purposes. The specific grade and purity should be confirmed with our sales team, but it is not represented as USP, BP, or EP grade.
How should (±)-2-Amino-4-phosphonobutyric acid be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation to prevent irritation to the respiratory tract, skin, and eyes (H315-H319-H335).
Is (±)-2-Amino-4-phosphonobutyric acid a controlled substance?
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The provided data does not indicate that (±)-2-Amino-4-phosphonobutyric acid is a controlled substance.
How is (±)-2-Amino-4-phosphonobutyric acid shipped?
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Tech Serve Solutions, as a global supplier and exporter, can ship this chemical internationally. Shipping methods comply with regulations for chemical transport.
How can I request a quote or sample?
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To request a quote or sample of (±)-2-Amino-4-phosphonobutyric acid, please contact the Tech Serve Solutions sales department through our website or by phone.
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