2-Amino-4-chloro-5-formyl-3-thiophenecarbonitrile
2-Amino-4-chloro-5-formyl-3-thiophenecarbonitrile (CAS: 104366-23-6) is a halogenated heterocyclic organic compound with the molecular formula C6H3ClN2OS and a molecular weight of 186.62 g/mol. This fine chemical serves as a valuable building block in organic synthesis, particularly for the construction of complex heterocyclic systems. Its aldehyde and nitrile functionalities, along with the thiophene core and chlorine substituent, offer diverse reactivity for medicinal chemistry and materials science research.
- IUPAC
- 2-Amino-3-cyano-4-chlorothiophene-5-carboxaldehyde
- Synonyms
- 2-Amino-3-cyano-4-chlorothiophene-5-carboxaldehyde

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of various organic compounds, particularly those containing thiophene rings. Its reactive functional groups facilitate diverse chemical transformations for creating novel molecular structures.
Medicinal Chemistry Research
A useful building block for the development of potential pharmaceutical agents. The thiophene scaffold is present in numerous biologically active molecules, making this compound a valuable starting point for drug discovery programs.
Materials Science
Can be employed in the synthesis of functional organic materials. Its structural features may contribute to unique electronic or optical properties when incorporated into larger molecular systems or polymers.
| Molecular weight | 186.62 |
|---|---|
| Empirical formula | C6H3ClN2OS |
| Assay | 90% |
| Storage temperature | 2-8°C |
| Melting point | 270-271 °C |


Hazard statements
- H301Toxic if swallowed
- H314Causes severe skin burns and eye damage
- H317May cause an allergic skin reaction
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2923 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 22-34-43 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-4-chloro-5-formyl-3-thiophenecarbonitrile used for?
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This compound is primarily used as a versatile building block in organic synthesis, particularly for creating complex heterocyclic structures relevant to medicinal chemistry and materials science research.
What is the CAS number and chemical formula for 2-Amino-4-chloro-5-formyl-3-thiophenecarbonitrile?
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The CAS number is 104366-23-6 and the chemical formula is C6H3ClN2OS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 90%. We do not represent this product as USP, BP, or EP grade. It is suitable for research and general chemical synthesis purposes.
How should 2-Amino-4-chloro-5-formyl-3-thiophenecarbonitrile be handled safely?
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This compound is classified as Danger, with hazards including H301 (Toxic if swallowed), H314 (Causes severe skin burns and eye damage), and H317 (May cause an allergic skin reaction). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection (e.g., N100 respirator), must be used. Handle in a well-ventilated area and follow strict safety protocols.
Is 2-Amino-4-chloro-5-formyl-3-thiophenecarbonitrile available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Amino-4-chloro-5-formyl-3-thiophenecarbonitrile.
How can I request a quote or sample?
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Please contact our sales team via the website or provide your requirements directly through the product page to request a quote or sample.
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