2-Amino-3-methyl-1-butanol
2-Amino-3-methyl-1-butanol (CAS: 16369-05-4) is a chiral amino alcohol with the linear formula (CH3)2CHCH(NH2)CH2OH and a molecular weight of 103.16 g/mol. This compound serves as a valuable building block in organic synthesis. Its applications include its use as a chiral nucleophile in complex antibiotic syntheses and in the preparation of specific heterocyclic compounds.
- IUPAC
- DL-Valinol
- Synonyms
- DL-Valinol
Synthesis of Pyrroleimines
2-Amino-3-methyl-1-butanol has been utilised in the synthetic pathways for preparing 1-allyl-2-pyrroleimines, demonstrating its utility in heterocyclic chemistry.
Chiral Nucleophile in Antibiotic Synthesis
The compound functions as a chiral nucleophile in the total synthesis of complex molecules, such as the benanomicin-pradimicin antibiotics, highlighting its role in stereoselective synthesis.
Synthesis of Crown Ethers
It has been employed as a homochiral guest compound in the synthesis of crown ethers that incorporate two chiral subunits, showcasing its application in host-guest chemistry.
| Molecular weight | 103.16 |
|---|---|
| Linear formula | (CH3)2CHCH(NH2)CH2OH |
| Assay | 97% |
| Boiling point | 75-77 °C/8 mmHg(lit.) |
| Density | 0.936 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4543(lit.) |
| Application | 2-Amino-3-methyl-1-butanol was used in the synthesis of 1-allyl-2-pyrroleimines1. It was also used as chiral nucleophile in the total synthesis of benanomicin-pradimicin antibiotics2. It was used as homochiral guest compound during synthesis of crown ethers containing two chiral subunits3. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 90 °C / 194 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Amino-3-methyl-1-butanol used for?
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2-Amino-3-methyl-1-butanol is used as a building block in organic synthesis, including the preparation of pyrroleimines, as a chiral nucleophile in antibiotic synthesis, and in the synthesis of crown ethers.
What is the CAS number and formula for 2-Amino-3-methyl-1-butanol?
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The CAS number is 16369-05-4, and the linear formula is (CH3)2CHCH(NH2)CH2OH.
What grade and purity does Tech Serve Solutions supply for 2-Amino-3-methyl-1-butanol?
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Tech Serve Solutions supplies 2-Amino-3-methyl-1-butanol with a minimum purity of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety precautions when handling 2-Amino-3-methyl-1-butanol?
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Handle with appropriate personal protective equipment, including a dust mask (N95 US type), eyeshields, and gloves. It is classified as an irritant, causing skin, eye, and respiratory irritation (H315-H319-H335).
How is 2-Amino-3-methyl-1-butanol packed and shipped?
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2-Amino-3-methyl-1-butanol is carefully packed and exported by Tech Serve Solutions in compliance with all relevant shipping regulations for chemical substances.
How can I request a quote or sample for 2-Amino-3-methyl-1-butanol?
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To request a quote or a sample of 2-Amino-3-methyl-1-butanol, please contact our sales department through the website or direct email.
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