2-(Allyldimethylsilyl)pyridine
2-(Allyldimethylsilyl)pyridine (CAS: 118722-54-6) is an organosilicon compound with the linear formula (CH2CHCH2)Si(CH3)2(C5H4N) and a molecular weight of 177.32 g/mol. This pyridine derivative serves as a valuable building block in chemical synthesis, particularly in organometallic chemistry. It participates effectively in palladium-catalyzed cross-coupling reactions, offering unique synthetic pathways for complex molecules.
- IUPAC
- Allyldimethyl(2-pyridyl)silane
- Synonyms
- Allyldimethyl(2-pyridyl)silane

Palladium-Catalyzed Cross-Coupling Reactions
Unlike many 2-pyridyl metal complexes, this compound is reactive in Pd-catalyzed cross-coupling reactions with aryl iodides when silver(I) oxide is present. This reactivity makes it useful for forming new carbon-carbon bonds.
Heterocyclic Synthesis
As a functionalised pyridine derivative, it can be employed in the synthesis of more complex heterocyclic structures. The presence of the allyldimethylsilyl group offers opportunities for further chemical transformations.
Organosilicon Chemistry
This compound is an example of an organosilicon reagent, suitable for research and development in organosilicon chemistry. Its structure allows for the introduction of both silicon and pyridine functionalities into target molecules.
| Molecular weight | 177.32 |
|---|---|
| Linear formula | (CH2CHCH2)Si(CH3)2(C5H4N) |
| Assay | 90% |
| Density | 0.913 g/mL at 25 °C |
| Refractive index | n20/D 1.5046 |
| Storage temperature | 2-8°C |
| Application | Unlike most 2-pyridyl metal complexes, this compound participates in Pd-catalyzed cross-coupling reactions with aryl iodides in the presence of silver(I) oxide.1 |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 71 °C / 159.8 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Allyldimethylsilyl)pyridine used for?
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2-(Allyldimethylsilyl)pyridine is used as a building block in chemical synthesis, particularly in palladium-catalyzed cross-coupling reactions and the preparation of heterocyclic compounds. It is also utilized in organosilicon chemistry.
What is the CAS number and chemical formula for 2-(Allyldimethylsilyl)pyridine?
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The CAS number is 118722-54-6 and the linear formula is (CH2CHCH2)Si(CH3)2(C5H4N).
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Allyldimethylsilyl)pyridine with an assay of 90%. We do not represent this product as USP, BP, or EP grade.
How should 2-(Allyldimethylsilyl)pyridine be handled safely?
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2-(Allyldimethylsilyl)pyridine is a Warning substance (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. Ensure good ventilation. Store at 2-8°C.
How is this chemical packed and shipped by TSS?
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Tech Serve Solutions exports fine chemicals globally. Specific packaging details for 2-(Allyldimethylsilyl)pyridine will be provided upon request, adhering to all relevant shipping regulations for hazardous materials.
How can I request a sample or quote for 2-(Allyldimethylsilyl)pyridine?
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To request a sample or a quote for 2-(Allyldimethylsilyl)pyridine, please contact our sales team through the website or by phone.
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