2-(Acetylthio)acetamide
2-(Acetylthio)acetamide (CAS 72370-26-4) is a sulfur-containing organic compound with the linear formula CH3COSCH2CONH2 and a molecular weight of 133.17 g/mol. This chemical serves as a valuable building block in organic synthesis. Its structure incorporates both a thioester and an amide functional group, making it amenable to various chemical transformations for the construction of more complex molecules. Supplied with an assay of 97%, it is suitable for research and development purposes.

Organic Synthesis Intermediate
2-(Acetylthio)acetamide acts as a versatile building block in the synthesis of diverse organic molecules. Its functional groups allow for participation in various coupling and modification reactions.
Thiol and Mercaptan Chemistry
As a protected thiol derivative, this compound is useful in reactions requiring a masked mercaptan functionality. It can be deprotected under specific conditions to reveal the reactive thiol group.
Chemical Research
Utilised in academic and industrial research settings to explore novel synthetic pathways and develop new chemical entities. Its specific structure can introduce sulfur into target molecules.
| Molecular weight | 133.17 |
|---|---|
| Linear formula | CH3COSCH2CONH2 |
| Assay | 97% |
| Melting point | 79-84 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(Acetylthio)acetamide used for?
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2-(Acetylthio)acetamide is primarily used as a building block and intermediate in organic synthesis and chemical research, particularly involving sulfur compounds and protected thiols.
What are the CAS number and formula for 2-(Acetylthio)acetamide?
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The CAS number is 72370-26-4, and the linear formula is CH3COSCH2CONH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-(Acetylthio)acetamide with an assay of 97%. We do not represent this product as meeting USP, BP, or EP pharmacopoeial standards.
What are the main hazards associated with 2-(Acetylthio)acetamide?
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2-(Acetylthio)acetamide is classified as a Warning (GHS07) with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection, should be used.
How is 2-(Acetylthio)acetamide shipped and exported by TSS?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-(Acetylthio)acetamide, adhering to all necessary shipping and export regulations.
How can I request a sample or quote for 2-(Acetylthio)acetamide?
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To request a sample or a quotation for 2-(Acetylthio)acetamide, please contact our sales team through the details provided on our website.
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