3-(Benzyldimethylammonio)propanesulfonate
3-(Benzyldimethylammonio)propanesulfonate (CAS 81239-45-4) is a zwitterionic compound with the molecular formula C6H5CH2N+(CH3)2CH2CH2CH2SO3− and a molecular weight of 257.35 g/mol. It is a valuable reagent in biochemical and proteomic applications, particularly for solubilizing membrane proteins and in electrophoresis techniques like SDS-PAGE. Its zwitterionic nature makes it effective in disrupting protein aggregation while maintaining biological activity.
- IUPAC
- 3-(N-Phenylmethyl-N,N-dimethylammonio)propanesulfonate,NDSB 256,PDA
- Synonyms
- NDSB 256PDA3-(N-Phenylmethyl-N,N-dimethylammonio)propanesulfonate

Membrane Protein Solubilization
This compound is employed to effectively solubilize membrane proteins, aiding in their purification and study. Its zwitterionic properties help to maintain protein structure and function during extraction.
Electrophoresis and Chromatography
Utilised in protein electrophoresis, including SDS-PAGE, and various chromatographic techniques. It assists in separating and analysing proteins by modifying their solubility and migration properties.
Proteomics Research
A key reagent in proteomics for the analysis of complex protein mixtures. It aids in sample preparation and can help reduce non-specific binding in certain assays.
Biochemical Assays
Serves as a zwitterionic detergent in various biochemical assays where mild solubilisation and minimal interference with biological activity are required.
| Molecular weight | 257.35 |
|---|---|
| Linear formula | C6H5CH2N+(CH3)2CH2CH2CH2SO3− |
| Assay | ≥99.0% (HPCE) |
| Solubility | H2O: soluble10 mg/mL, clear, colorless |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Cation traces | Ca: ≤10 mg/kgCd: ≤5 mg/kgCr: ≤5 mg/kgCu: ≤5 mg/kgFe: ≤5 mg/kgK: ≤50 mg/kgMg: ≤5 mg/kgMn: ≤5 mg/kgNa: ≤50 mg/kgNi: ≤5 mg/kgPb: ≤5 mg/kgZn: ≤5 mg/kg |
| Anion traces | chloride (Cl-): ≤50 mg/kgsulfate (SO42-): ≤50 mg/kg |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | zwitterionic |
|---|---|
| Product Line | BioXtra |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Benzyldimethylammonio)propanesulfonate used for?
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3-(Benzyldimethylammonio)propanesulfonate is primarily used in biochemical research for membrane protein solubilisation and in electrophoresis techniques like SDS-PAGE and chromatography. It also finds application in proteomics and other biochemical assays requiring a mild, zwitterionic detergent.
What are the CAS number and chemical formula for 3-(Benzyldimethylammonio)propanesulfonate?
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The CAS number for 3-(Benzyldimethylammonio)propanesulfonate is 81239-45-4. Its linear formula is C6H5CH2N+(CH3)2CH2CH2CH2SO3−, and its molecular weight is 257.35 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-(Benzyldimethylammonio)propanesulfonate with an assay of ≥99.0% (HPCE). TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 3-(Benzyldimethylammonio)propanesulfonate be handled safely?
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When handling 3-(Benzyldimethylammonio)propanesulfonate, it is important to wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. This compound is classified with WGK Germany 3, indicating it is hazardous to water.
How is 3-(Benzyldimethylammonio)propanesulfonate packed and shipped?
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3-(Benzyldimethylammonio)propanesulfonate is available for expert packing, shipping, and global export by Tech Serve Solutions, adhering to all relevant regulations for chemical transport.
How can I request a sample or a quote for 3-(Benzyldimethylammonio)propanesulfonate?
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To request a sample or a quotation for 3-(Benzyldimethylammonio)propanesulfonate, please contact the Tech Serve Solutions sales team through our website or by phone.
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