3-(N,N-Dimethylpalmitylammonio)propanesulfonate
3-(N,N-Dimethylpalmitylammonio)propanesulfonate (CAS: 2281-11-0), also known as Palmityl sulfobetaine, is a zwitterionic detergent with a molecular weight of 391.65 g/mol. It is utilised in various analytical and biochemical applications, including protein extraction for chromatographic and spectroscopic analysis. This compound is valuable for solubilising membrane proteins and has been employed in research studies investigating enzyme characterisation and transport mechanisms.
- IUPAC
- 3-(N,N-Dimethylhexadecylammonio)propanesulfonate,3-(Hexadecyldimethylammonio)propanesulfonate,3-(Palmityldimethylammonio)propanesulfonate,Palmityl sulfobetaine,SB3-16
- Synonyms
- SB3-16Palmityl sulfobetaine3-(N,N-Dimethylhexadecylammonio)propanesulfonate3-(Hexadecyldimethylammonio)propanesulfonate3-(Palmityldimethylammonio)propanesulfonate
Protein Solubilisation and Extraction
This zwitterionic detergent is employed for the extraction and solubilisation of proteins. It is particularly useful for preparing proteins for analysis using techniques such as chromatography, mass spectrometry, and electrophoresis.
Biochemical Research
3-(N,N-Dimethylpalmitylammonio)propanesulfonate has been used in scientific studies to investigate biological processes, such as the characterisation of rat dihydroceramide desaturase and the inhibition of mitochondrial carnitine–acylcarnitine translocase.
Analytical Applications
As an analytical reagent, it aids in various separation and characterisation techniques, supporting researchers in understanding complex biological systems and molecules.
| Molecular weight | 391.65 |
|---|---|
| Linear formula | CH3(CH2)15N+(CH3)2CH2CH2CH2SO3- |
| Assay | ≥98% (TLC) |
| Application | 3-(N,N-Dimethylpalmitylammonio)propanesulfonate has been used in a study to assess the characterization of rat dihydroceramide desaturase. 1 It has also been used in a study to investigate the inhibition of mitochondrial carnitine–acylcarnitine translocase by sulfobetaines. 2 It is also used for extraction of proteins for analysis by chromatography, mass spectroscopy, and electrophoretic methods. |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | zwitterionic |
|---|---|
| Mol Wt | micellar avg mol wt 60,700 |
| Conductivity | ≤10 μmho per cm at 24 °C (0.05 M aqueous solution) |
| Aggregation Number | 155 |
| Cmc | 0.01-0.06 mM(20-25°C) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(N,N-Dimethylpalmitylammonio)propanesulfonate used for?
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3-(N,N-Dimethylpalmitylammonio)propanesulfonate is used for protein extraction and solubilisation for analysis by chromatography, mass spectroscopy, and electrophoretic methods. It is also utilised in biochemical research, including studies on enzyme characterisation and transport mechanisms.
What are the CAS number and molecular formula for this compound?
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The CAS number is 2281-11-0. The linear formula is CH3(CH2)15N+(CH3)2CH2CH2CH2SO3-.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-(N,N-Dimethylpalmitylammonio)propanesulfonate with an assay of ≥98% (TLC). We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
What are the safety considerations for handling this chemical?
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This compound is classified with GHS07 symbol and a Warning signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Ensure adequate ventilation.
How is 3-(N,N-Dimethylpalmitylammonio)propanesulfonate packed and shipped?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific packaging and shipping details are available upon request and are handled in compliance with international regulations.
How can I request a quote or sample?
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To request a quote or sample of 3-(N,N-Dimethylpalmitylammonio)propanesulfonate, please contact our sales team through the website or by phone.
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